Results 181 to 190 of about 3,895,024 (310)

Seroprevalence and associated risk factors for feline panleukopenia virus infection among managed giant pandas in China. [PDF]

Vet Res
Li Y, Jia R, Zhang H, Chen X, Zeng J, Lan J, Yue C, Zhang D, Huang W, Yang W, Fan X, Xia X, Hou R, Feng N, Liu S.   +14 more
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

History of conulariid research

Journal of the Palaeontological Society of India, 2009
Consuelo Sendino, Jill Darrell
doaj   +1 more source

Reflections of "New" Geographies: A Brief Glimpse at Pre-Modern Cartography

Open Rivers, 2017
Marguerite Ragnow
doaj   +1 more source

Combined effects of maternal periconceptional environmental exposures and infant cardiac transcription factor polymorphisms on congenital heart disease risk. [PDF]

Ann Med
Wei J, Huang P, Chen L, Yang T, Wang T, Li Z, Chen L, Qin J.   +7 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Editorial: History of Chemoattractant Research

Frontiers in Immunology, 2015
Bernhard eMoser
doaj   +1 more source

Family history of diabetes and glycemic progression: A propensity score-based analysis using health checkup data. [PDF]

PLoS One
Oh S, Kim S, Yun J, Min JK, Jee HJ, Heo TY.   +5 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Exploring current cancer screening practices and guidelines for adults under age 50 in the United States. [PDF]

Front Public Health
Reedy JM, Borstelmann NA, Giri VN.
europepmc   +1 more source