Results 111 to 120 of about 106,644 (264)

FUCA2 Sustains AKT Signaling and Suppresses Senescence by Antagonizing FUT3‐Mediated ErbB3 Fucosylation in Lung Adenocarcinoma

Advanced Science, EarlyView.
ABSTRACT While targeted therapies have improved outcomes in lung adenocarcinoma (LUAD), many patients still lack targetable mutations. Here, we identified alpha‐L‐fucosidase 2 (FUCA2) as a crucial driver of LUAD by preventing cellular senescence. Mechanistically, through the restriction of fucosyltransferase 3 (FUT3)‐mediated α‐1,3‐fucosylation of ...
Lu Chen, Jintao Guo, Fei Li, Mingjie Gao, Runyang Li, Zhaozhang Huang, Yaolin Zheng, Chunyi Gao, Jihuan Hou, Qiang Yu, Bowen Zheng, Xuemei Chen, Wenqing Zhang, Xiaoting Hong, Yali Zheng, Daxuan Wang, Qiyuan Li, Tianhui Hu, Yan‐yan Zhan   +18 more
wiley   +1 more source

Visualization Analysis of Research Status and Hot Spots of Phosphine Based on CiteSpace (2004—2023)

Liang you shipin ke-ji
Phosphine plays an important role in chemistry, materials science, physics, agriculture and other fields, and is widely used in semiconductor, plastic industry and storage fumigation. In order to systematically sort out the research hotspots of phosphine
ZHANG Hui-yan, LI Yan-yu, ZI Jia-yu, CHEN Xin, CUI Peng-cheng, ZHOU Gui-ming, TAO Hai-hua, TIAN Xiao-wei   +7 more
doaj   +1 more source

Global Research Hotspots and Progress on Acrylamide: Visualization Analysis

Environmental Health Insights
Acrylamide is a contaminant prevalent in many commonly consumed foods, contributing to unavoidable human exposure. It is recognized as likely to be carcinogenic to humans as well, provoking global concerns. Numerous studies have investigated the impacts of acrylamide formation on food and drink, nutrition, and health.
Shaher Zyoud, Sa’ed H. Zyoud
openaire   +3 more sources

From Ambition to Action: Barriers and Enablers for the Inclusion of Indigenous Peoples and Local Communities in the Kunming–Montreal Biodiversity Framework and the Role of Non‐State Bridge Organizations

Advanced Science, EarlyView.
Graphical abstract illustrating the transition from global biodiversity ambition to on‐the‐ground implementation of the Kunming–Montreal Global Biodiversity Framework after COP16, highlighting the roles of governments, non‐state actors, scientific knowledge systems, and resource mobilization in achieving transformative biodiversity outcomes.
Susan Enechojo Ogbe, Jinfeng Zhou, Linda Wong, Jiachen Gao   +3 more
wiley   +1 more source

Research hotspots and frontiers of alcohol and epilepsy: A bibliometric analysis

Neuropsychopharmacology Reports
AbstractPurposeAlcohol is implicated in epileptogenesis and seizures attack. An increasing number of studies about alcohol and epilepsy have been published. We aimed to assess research trends and hot spots in the field of alcohol and epilepsy.Patients and MethodsLiterature concerning alcohol and epilepsy was systemically searched through the Web of ...
Wenhui Liu, Huan Li, Simei Lin
openaire   +3 more sources

Electric‐Current‐Induced Phase Transformation in Cu6Sn5 Below Its Equilibrium Transition Temperature

Advanced Science, EarlyView.
Electric current induces a monoclinic‐to‐hexagonal phase transformation in Cu6Sn5 at a measured bulk temperature of ∼120°C, below the equilibrium transition temperature. Ex situ synchrotron x‐ray diffraction, TEM, and matched thermal controls show that current stressing promotes the formation of a retained hexagonal η‐phase post‐stress state not ...
Shih‐kang Lin, Shubhayan Mukherjee, Yu‐chen Liu, Jun Mizuno   +3 more
wiley   +1 more source

Integrated Single‐Cell and Spatial Analysis Reveals a Metabolic‐Immune Axis Driving Aortic Dissection

Advanced Science, EarlyView.
Single‐cell and spatial profiling of 110 human thoracic aortic samples reveals a stromal–immune circuit driving aortic dissection. An elastin‐rich fibroblast subset is depleted with age and markedly reduced in disease, weakening aortic wall integrity.
Jing Tao, Huanjie Yang, Jiahui Yong, Xueting Chen, Qiang Zhao, Xueli Wu, Lei Yan, Li Pang, Fan Luo, Mengjun Yu, Shanshan Pan, Deyang Li, Rouxi Chen, Juan Wang, Zhensheng Dong, Fan Yang, Yue Wang, Yang Chen, Hongjian Zheng, Zhimin Yang, Zijie Wang, Karsten Kristiansen, Hui Peng, Xiaodong Fang, Juan Shen, Yining Yang   +25 more
wiley   +1 more source

Bibliometric analysis of nursing theory related research based on CNKI database

Huli yanjiu, 2022
ZHU Ruifang, WANG Yaping, HAN Shifan, DUAN Zhiguang   +3 more
doaj  

Research hotspots and frontiers of cluster headaches: a bibliometric analysis

Frontiers in Neurology
BackgroundExtensive research on cluster headaches (CHs) has been conducted worldwide; however, there is currently no bibliometric research on CHs. Therefore, this study aimed to analyze the current research hotspots and frontiers of CHs over the past decade.MethodsRaw data on CHs was obtained from the Web of Science Core Collection database from 2014 ...
Qiangjian Mao, Shiqi Xu, Yuqing Wang, Desheng Wu, Guomin Huang, Ziru Li, Xiaoming Zhang, Zhenhai Chi   +7 more
openaire   +3 more sources

Tumor‐Infiltrating mregDCs Restrain Anti‐Tumor Immunity in Early Relapse HCC

Advanced Science, EarlyView.
Tumor‐infiltrating mregDCs are regulated by the TNFR2‐non‐canonical NF‐κB axis, which is mediated by TNF‐α secreted by CD161+CD8+ T cells. These mregDCs recruit CD161+CD8+ T cells via the CCL20‐CCR6 axis, forming a positive feedback loop that enhances immunosuppression, promotes early recurrence of HCC, and further confirms TNFR2 as a key therapeutic ...
Zefan Zhang, Lin Ding, Yu Zhong, Haokang Feng, Linglong Huang, Waidong Huang, Chunqing Wang, Arne Östman, Beili Wang, Jian Zhou, Jia Fan, Wei Guo, Liang Wu, Yunfan Sun   +13 more
wiley   +1 more source