Results 31 to 40 of about 67,152,869 (252)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Hotspot Zuidplaspolder: Climate adaptation in the Zuidplaspolder [PDF]
, 2008 Building at the lowest point in the Netherlands, in the Zuidplaspolder, is viewed as a challenge and not something that is impossible. The Xplorelab approach in the Hotspot Zuidplaspolder project is a combination of research, implementation of ideas into
Pelt, F., van +5 more
core
, 2023 An internet hotspot network is a basic need for professional agencies, including the Daarul Qur'an Tahfizh Islamic Boarding School, Tangerang. Healthy internet features and ad blocking are also installed on the internet network as a security measure ...
Muchlis +2 more
core +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Evolution of a hotspot genus: geographic variation in speciation and extinction rates in Banksia (Proteaceae) [PDF]
, 2016 BACKGROUND Hotspots of angiosperm species richness and endemism in Mediterranean-climate regions are among the most striking, but least well-understood, geographic patterns of biodiversity.
Pratt, Renae, Cardillo, Marcel
core +1 more source
Hubungan Curah Hujan dan Titik Panas (Hotspot) Kebakaran di Hutan Lindung Gambut (HLG) Londerang, Provinsi Jambi [PDF]
, 2021 Jambi is one of the provinces that has high risk of forest fires in Indonesia.HLG Londerang is one of the protected peatland forests in Jambi that burned greatly in 2015. Precipitation become one of the climate factor that is affecting fires risk.
Husni, Rahmadika Fairuz +3 more
core +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Pendaftaran pengguna layanan hotspot berbasis web Pada hotspot mikrotik dan freeradius [PDF]
, 2012 Abstraksi : Lokasi yang memberikan akses internet menggunakan jaringan nirkabel atau lebih dikenal sebagai hotspot sudah sangat umum ditemui saat ini.
Wicahyanto, Arif +1 more
core +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Frontiers in OncologyObjectiveTo explore the current status of therapeutic drug monitoring (TDM) research on anticancer drugs, analyze research hotspots and trends, and provide insights and references for future studies.MethodsData were retrieved from the Web of Science Core
Can Qian +9 more
doaj +1 more source