Results 131 to 140 of about 106,644 (264)

Research on the Hotspots of Ecological Sports [PDF]

Proceedings of the 2016 International Conference on Education, Management Science and Economics, 2016
openaire   +1 more source

SIRT6‐Mediated Deacetylation of ATF3 Promotes Silica‐Induced Lung Fibrosis by Enhancing its Nuclear Import via Binding to Importin α

Advanced Science, EarlyView.
SIRT6‐mediated ATF3 acetylation drives MGARP transcription and mitochondrial dysfunction in macrophages, promoting macrophage senescence and pulmonary fibrosis. Mechanistically, HSP70/Importin α competitively binds to ATF3, modulating its nuclear translocation.
Demin Cheng, Wenxia Bu, Fengxu Wang, Yueyuan Jin, Rongzhu Liu, Rui Zhao, Xuehai Wang, Mengna Jiang, Jinping Shen, Xinhang Cheng, Zuming Chen, Li Zhu, Jinlong Li, Zhenzhong Ge, Shichen Miao, Haotian Xu, Xiaoyu Zhou, Dongming Wang, Xinyuan Zhao   +18 more
wiley   +1 more source

Mitochondrial Carrier SLC25A13 Drives Ferroptosis Resistance and Immune Evasion via a STAT3–IFI6 Circuit in Breast Cancer

Advanced Science, EarlyView.
SLC25A13 is identified as an immunometabolic driver of triple‐negative breast cancer that sustains ferroptosis resistance and immune evasion through a STAT3–IFI6 circuit. Pharmacologic degradation of SLC25A13 restores ferroptosis sensitivity and enhances anti‐PD‐1 efficacy, highlighting a strategy to convert immune‐cold tumors into immunotherapy ...
Yingze Zhu, Yuhan Tang, Yingcui Chen, Zhuoqi Zhang, Yige Lu, Xinyue Wang, Qiyuan Shi, Wenhui Zhao, Hui Pang   +8 more
wiley   +1 more source

Research Progress on Hotspots and Trends of Eco-hydrology

Renmin Zhujiang
Eco-hydrology is an interdisciplinary field that combines ecology and hydrology, primarily focusing on the interactions between water and ecosystems on Earth. To explore the current state and hotspots of research in the field of eco-hydrology, this study
HUANG Wei, JI Yong, WANG Pengyang, LI Zhuojun, ZHANG Jie, YE Fangqi   +5 more
doaj  

Single‐Cell Annotation and Localization via Integrating Spatial Transcriptomics Maps the Mouse Ocular Atlas and RAO Dynamics

Advanced Science, EarlyView.
We developed the ASCAL pipeline, integrating complementary spatial transcriptomics, to construct a high‐fidelity mouse whole‐eye single‐cell atlas. Applying ASCAL to a retinal artery occlusion (RAO) model revealed spatially restricted immune activation localized to the ganglion cell layer and the selective depletion of a translationally active, outer ...
Chen Du, Yinming Li, Ziyue Li, Yuedan Wang, Shaopeng Li, Yijie Wang, Yingying Qu, Bingyang Lv, Ying Li, Ting Chen, Yu Zhou, Xuan Xiao   +11 more
wiley   +1 more source

Synergistic Stabilization of Potassium Metal Anodes Through Orange‐Peel Elimination and Robust Solid–Electrolyte Interphase Formation

Advanced Science, EarlyView.
Synergistic control of surface uniformity and solid–electrolyte interphase robustness regulates potassium deposition, suppressing dendritic growth and enabling uniform, dense potassium plating. This combined strategy promotes stable interfacial chemistry and homogeneous electric‐field distribution, leading to enhanced reversibility and long‐term ...
Pan He, Yupei Han, Yundong Zhou, Ruhan He, Rui Xu, Yunlong Zhao, Junjun Wang, Wanjun Ren, Matthew Hopper, Qinyou An, Denys Makarov, Ian S. Gilmore, Liqiang Mai, Yang Xu   +13 more
wiley   +1 more source

Research Hotspot and Trend Analysis of Earth-Rockfill Dam Stability Based on Knowledge Map

Renmin Zhujiang
Since the 20th century, earth-rockfill dam instability accidents have occurred frequently all over the world. In order to systematically summarize the current status and hotspots of research on earth-rockfill dam stability and analyze the future ...
WANG Luoxi, HAN Peifeng, LI Yan'ang, YANG Guocheng, QIU Hongzhi   +4 more
doaj  

Large Temperature‐invariant Anomalous Nernst Effect in Non‐collinear Antiferromagnet Mn3Pt

Advanced Science, EarlyView.
Based on the noncollinear antiferromagnetic Mn3Pt thin films, the composition‐tunable Mn‐3d orbital states directly govern the Berry curvature. As a result, a giant and temperature‐invariant anomalous Nernst coefficient of 0.71 µV/K is achieved under Mn‐rich conditions.
Pengwei Gong, Xiaolin Zhang, Wei Zhu, Mingzhi Wang, Chang Pan, Aoqi Xu, Yandong Guo, Yuheng Li, Jiaxin Chen, Yanchang Zhou, Zhong Shi, Dingfu Shao, Liang Liu, Shiming Zhou, Yicheng Guan, Ruiqing Cheng, Xuepeng Qiu   +16 more
wiley   +1 more source

Intramolecular Interactions between Folded and Disordered Regions Shape Ubiquilin Structure and Function

Advanced Science, EarlyView.
Ubiquilin (UBQLN), like many other human proteins, contains both well‐folded and disordered regions. Here, we show that intramolecular interactions between disordered regions and folded domains modulate between open and closed topologies of UBQLN proteins, altering their structure and function.
Jessica K. Niblo, Nirbhik Acharya, Maxwell B. Watkins, Carlos A. Castañeda, Shahar Sukenik   +4 more
wiley   +1 more source

Synergistic Enhancement of Electrical‐Thermal Properties in KH550/G‐POSS Functionalized BN/Epoxy Composites for High‐Frequency Transformer Insulation

Advanced Science, EarlyView.
A BN@G‐POSS/EP nanocomposite is developed for high‐frequency transformer insulation in power electronic transformers. Through synergistic interface engineering, it simultaneously enhances thermal conductivity, reduces viscosity, and improves electro‐thermal stability.
Jun Jiang, Shaojie Luo, Dezhi Cui, Zeya Huang, Shuai Jiang, Renli Fu, Yuan Wang   +6 more
wiley   +1 more source