Results 41 to 50 of about 106,704 (264)

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Research Hotspots of Regional Resilience and the Visualization of Research Frontiers

open access: yesRedai dili, 2021
As a hot regional research realm, regional resilience provides a new research perspective toward regional sustainable development. At the same time, regional resilience is also an important research paradigm of sustainability science. Based on literature from a core database (Web of Science) launched between 1991 and 2019 on the topic of "regional ...
Han Zenglin, Zhu Wenchao, Li Bo
openaire   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Mapping the relationship between alcohol use disorder and gut microbiota: a 20-year bibliometric study

open access: yesFrontiers in Microbiology
BackgroundAlcohol use disorder (AUD) is a psychiatric disorder that is widespread worldwide. Alcohol use is a significant contributor to the global burden of death, disability and disease.
Ao Xiang   +6 more
doaj   +1 more source

Research hotspot and trend analysis of integrated care for older people based on CiteSpace

open access: yesHuli yanjiu, 2022
ObjectiveIt analyzed the hotspot and trend of integrated care research for older people in recent 10 years,in order to provide references for the development of integrated care research for the older people in China.MethodsLiteratures related to ...
LI Wenjun   +6 more
doaj  

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

The research trends and hotspots of claudins in the field of cancer

open access: yesCell Adhesion & Migration
Claudins (CLDNs), as the key components of tight junctions, have been implicated as key factors in carcinogenesis and metastasis. A total of 1720 publications on CLDNs in the field of cancer were published from January 2005 to December 2022. The United States dominates the research on CLDNs in cancer, followed by China.
Weixin Jing   +4 more
openaire   +3 more sources

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao   +6 more
wiley   +1 more source

The Price of Precision: A Critical Review of Molecular Diagnostics in Glioma, From Guidelines to Global Disparities

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
wiley   +1 more source

Vicissitudes and prospects of green roof research: a two-decade systematic bibliometric review

open access: yesFrontiers in Ecology and Evolution
Urban green roofs have emerged as an innovative nature-based solution for enhancing urban sustainability and resilience. Based on the Web of Science Core Collection database, the scholarly papers on green roofs published in the past two decades were ...
Chunping Xie, Dawei Liu, C. Y. Jim
doaj   +1 more source

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