Results 211 to 220 of about 50,210,574 (305)

Mutation Spectrum and Novel Rare Variants in a Han Chinese Hearing Loss Cohort Using a Tiered Sequencing Strategy. [PDF]

Mol Genet Genomic Med
Zhang Y, Yuan S, Wan Y, Li T, Xu L, Yang W, Niu C.   +6 more
europepmc   +1 more source

Atomistic Kinetics of Dislocation‐Mediated Grain Growth in Monolayer MoS2

Advanced Science, EarlyView.
Atomic‐resolution in‐situ heating microscopy directly visualizes dislocation‐mediated grain boundary migration and grain growth in monolayer MoS2. Mobile grain boundaries migrate through collective motion of Mo 5|7 dislocations, whereas S 5|7 defects remain largely immobile.
Chang‐Won Choi, Min‐Yeong Choi, Tao Du, Jinho Rhee, Seokho Moon, Yeon‐Seo Nam, Xiaoyan Lu, Jong Kyu Kim, Jungwon Park, Moon‐Ho Jo, Cheol‐Joo Kim, Si‐Young Choi   +11 more
wiley   +1 more source

Triggered Calcium Lightning Programs Cochlear Development. [PDF]

Exploration (Beijing)
Ma Q, Wang HP, Jiang YM, Lai K, Li MX, Zhang Z, Gong LN, Lai JW, Su KM, Wang LY, Wang H, Yin SK, He H, Shi HB.   +13 more
europepmc   +1 more source

Chemotherapy‐Activated GSK3β‐DNMT1 Signaling Upregulates CD47 to Evade Macrophage Phagocytosis and Drive Temozolomide Resistance in Glioblastoma

Advanced Science, EarlyView.
Temozolomide treatment activates GSK3β, driving DNMT1 phosphorylation, destabilization, and CD47 promoter hypomethylation in glioblastoma. This epigenetic shift upregulates CD47, enabling TMZ‐treated GBM cells to evade macrophage phagocytosis, survive chemotherapy, and acquire resistance.
Jie Li, Shuai Ying, Yi Zhang, Jingjing Wang, Quan Wan, Lingli Gong, Daxing Xu, Zhenkun Yang, Hongnian Lu, Ying Yin, Xiangming Fang, Zhening Pu   +11 more
wiley   +1 more source

Feasibility and Acceptability of a Digital Indoor Air Quality Monitor Among Children with Asthma. [PDF]

JMIR Pediatr Parent
Orr O, Honegger K, Sanchez L, Bhat K, Nimmagadda S, Kan K.   +5 more
europepmc   +1 more source

Targeting the CRYAB/β‐Catenin Axis with an MMP‐9‐Responsive Hydrogel Disrupts CTC Clusters to Suppress Progression of Hepatocellular Carcinoma after Radiofrequency Ablation

Advanced Science, EarlyView.
The graphical abstract illustrates that sublethal thermal stress after iRFA upregulates the chaperone CRYAB in residual HCC cells, which stabilizes β‐catenin and drives a dual pathological program, including EMT and N2‐TAN polarization, thereby leading to heterotypic CTC cluster formation. The MMP‐9‐responsive hydrogel (XB@Gel) delivers XAV‐939 and BMS‐
Hui Chen, Danni Yang, Songying Pi, Yuhan Liu, Hongbin Huang, Feile Ye, Yuhong Lin, Zhongzhen Su, Yongquan Huang   +8 more
wiley   +1 more source

Clinically actionable genomic alterations in breast cancer brain metastases. [PDF]

ESMO Open
Griguolo G, Collesei A, Lazzarini E, Bottosso M, Dieci MV, Fineberg S, Bauchet L, Landa G, Miglietta F, Jacob J, Rigau V, La Commare M, Trovò L, Fassan M, Jacot W, Dei Tos AP, Indraccolo S, Darlix A, Guarneri V.   +18 more
europepmc   +1 more source

Amphibious Movement of Microrobots Inspired by Water Spiders

Advanced Science, EarlyView.
Inspired by the water strider, a novel microrobot is designed to maintain amphibious mobility in complex environments. It retains the ability to traverse the air‐liquid interface and perform directional movement within sophisticated, multifaceted environments, including complex gastric wall structures, with precise controllability.
Xiao Hu, Run Ouyang, Zhuhao Shi, Wanqiong Tao, Zuchao Zhu, Peifeng Lin, Jianzhong Lin, Luca Brandt   +7 more
wiley   +1 more source

On the origin of PRDM9-guided recombination hotspots. [PDF]

Proc Natl Acad Sci U S A
Úbeda F, Bürger R, Fyon F.
europepmc   +1 more source

Biosynthesis of Spatially Differentiated Cellulose for Flexible All‐in‐one Supercapacitors

Advanced Science, EarlyView.
Spatially differentiated bacterial cellulose is grown by oxygen‐guided biosynthesis to form dense surface regions connected by an open fibrillar interlayer. This architecture supports electroactive material loading, ion transport, and mechanical stability in an all‐in‐one supercapacitor, showing how biological assembly can create device‐ready ...
Xin Shu, Yi Lu, Xuetong Shi, Zhangmin Wan, Peijin Jiang, Minke Yang, Qingshi Tu, Orlando J. Rojas   +7 more
wiley   +1 more source