Results 241 to 250 of about 50,210,574 (305)

A conserved small RNA-generating gene cluster undergoes sequence diversification and contributes to plant immunity. [PDF]

Nat Commun
Feng L, Hou Y, Toghani A, Wang Z, Tang B, Atkinson N, Li H, Qiao Y, Wang Y, Hua J, Zhai J, Ma W.   +11 more
europepmc   +1 more source

Sonogenetics Nanomedicine Activates the cGAS‐STING Pathway for Immunotherapy of Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
A HER3‐targeted sonogenetic lipid nanoparticle platform is developed for triple‐negative breast cancer therapy. An AI‐designed miniprotein inhibits HER3 signaling, while TRPV4 and NFAT‐responsive IL‐15 plasmids enable ultrasound‐controlled calcium signaling and cytokine expression. The system induces Ca2+ overload, ROS generation, mitochondrial damage,
Junya Song, Yan Liu, Shifeng Zhao, Cheng Zhu, Hongchang Guo, Jin Chang, Jun Kang   +6 more
wiley   +1 more source

Conservation and Targeted Wild Tending of <i>Schisandra chinensis</i> Under Global Change: Informed by SDMs and Fingerprint Analysis of Climate-Land-Composition Responses. [PDF]

Biology (Basel)
Duan D, You M, Li M, Li X, Xu H, Zhang B, Zhang X.   +6 more
europepmc   +1 more source

Multimodal Imaging of Hypoxia, Metabolism and pH in Feline Sarcoma Using Hyperpolarized 13C MRI and PET

Advanced Science, EarlyView.
This work presents a clinically deployable simultaneous PET/MRI workflow which integrates hyperpolarized 13C imaging of metabolism and extracellular pH with [18F]FMISO PET to characterize hypoxia, acidosis, and metabolic reprogramming in feline sarcoma.
Martin Grashei, Tanja Groll, Stephanie Kahl, Silke Baer, Elisabeth Bliemsrieder, Frits H. A. van Heijster, Andre Wendlinger, Pascal Wodtke, Jorge Cabello, Susan Notohamiprodjo, Christian Lohrmann, Markus Schwaiger, Wolfgang A. Weber, Katja Steiger, Andrea Meyer‐Lindenberg, Johannes Hirschberger, Christine Baumgartner, Franz Schilling   +17 more
wiley   +1 more source

Genome-Wide Integration Site Profiling of Multi-Component CAR T-Cell Engineering Systems with ADA1/CD26 Co-Transduction. [PDF]

Biomedicines
Song K, Hu Y, Song X.
europepmc   +1 more source

Arthropod‐Inspired Miniature Modular Vibration Direct‐Drive Robot With Untethered Locomotion

Advanced Science, EarlyView.
This work presents an arthropod‐inspired untethered miniature modular vibration direct‐drive robot. By utilizing standardized driving units and nested locking interfaces, on‐demand reconfiguration into quadruped, hexapod, octopod, and circular morphologies is achieved.
Shijing Zhang, Ziteng Liu, Youwei Liu, Dehong Wang, Yingxiang Liu   +4 more
wiley   +1 more source

Expanding the mitochondrial genomic toolkit for Polyneoptera: New mitogenomes and evaluation of reduced marker sets for phylogeny and DNA barcoding. [PDF]

Genet Mol Biol
Romão HAA, Corvalán LCJ, Carneiro JA, Santos DDFD, Nunes R, Dias RO.   +5 more
europepmc   +1 more source

Analysis of the current status and hotspots in the research of tibial osteomyelitis

Asian Journal of Surgery
Xiaohu Chang, Miao Shi, Jinshu Wang, Zhuodong Fu   +3 more
openaire   +3 more sources

Self‐Healing UPy‐Functionalized Polyethylene Networks: A Robust Platform for Resilient and High‐Performance Lithium Battery Separators

Advanced Science, EarlyView.
Self‐healing separators are developed by grafting ureidopyrimidinone (UPy) quadruple hydrogen‐bonding motifs onto PE‐HEMA copolymers, blended with high‐MW PEO via solvent‐free hot‐pressing. The dynamic UPy network enables autonomous healing, restoring functionality after short circuits.
Daniele Callegari, Arkadiusz Zych, Roberta Pinalli, Enrico Dalcanale, Eliana Quartarone   +4 more
wiley   +1 more source

Mapping Meiotic Recombination DNA Double-Strand Breaks (DSBs) Hotspots -Methodological Advances and Challenges. [PDF]

Adv Genet (Hoboken)
Bao J.
europepmc   +1 more source