Results 31 to 40 of about 107,666 (263)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Research hotspots and trends in intrinsic capacity of older people in the context of population aging based on CiteSpace

Frontiers in Aging
ObjectiveTo employ bibliometrics to identify the research hotspots and development trends of the intrinsic capacity of older people, thereby providing novel insights for future studies on the management of intrinsic capacity in older adults and further ...
Minhua Ren, Hongtao Guo, Ye Tian, Yingjie Guo, Wanjun Guo, Liangjin Zhu   +5 more
doaj   +1 more source

Review of the development of digital earth research during 1998–2015 based on a bibliometric analysis

International Journal of Digital Earth, 2017
Since Al Gore created the vision for Digital Earth in 1998, a wide range of research in this field has been published in journals. However, little attention has been paid to bibliometric analysis of the literature on Digital Earth.
Zhen Liu, Changlin Wang, Qiao Lin, Yang Liu   +3 more
doaj   +1 more source

Research on hotspots and trends of tectonic geomorphology in China： A perspective of Chinese bibliometrics analysis

地震科学进展, 2021
As a new discipline in the field of earth science，tectonic geomorphology has unique significance and scientific connotation of resources and environment.
Ziyue Shi, Cunlin Xin, Jingjing Wang, Haibo Liu, Xin Liu, Lidong Zhu   +5 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

The Evolution, Hotspots, and Trends in Research on Facilities of Combined Medical and Nursing Care for the Elderly

Buildings, 2022
With the significant increase in global ageing and its derivative risks, governments and academic communities have been widely concerned with research on facilities of combined medical and nursing care for the elderly (FCMNCE).
Zhe Chen, Qiang Yao, Na An
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Unveiling the complex networks of urban tree diversity research: A global perspective

Ecology and Evolution
Ecosystem services offered by urban forests must be proactively managed to remain diverse and sustainable. Recent research findings deserve a systematic synthesis to elucidate inherent knowledge structures and dynamics.
Chunping Xie, Shuifei Chen, Dawei Liu, Chi Yung Jim   +3 more
doaj   +1 more source

Bibliometric Analysis of the Research (2000–2020) on Land-Use Carbon Emissions Based on CiteSpace

Land, 2023
Carbon emissions are critical to climate change, and land-use change is an essential source of growth in carbon emissions. Research on land-use carbon emissions has become one of the hotspots in academic research.
Xiaoping Li, Sai Hu, Lifu Jiang, Bing Han, Jie Li, Xuan Wei   +5 more
doaj   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source