Results 41 to 50 of about 50,210,574 (305)

Moving hotspots [PDF]

open access: yes, 2001
The assumption that stationary hotspots underlie the Earth’s lithospheric plates has been most important in the development of the theory of plate tectonics. According to the fixed hotspot hypothesis seamount trails are formed by volcanism penetrating the
Antretter, Maria
core   +1 more source

Research hotspots and trends in therapeutic drug monitoring of anticancer drugs: a 1990–2024 bibliometric analysis

open access: yesFrontiers in Oncology
ObjectiveTo explore the current status of therapeutic drug monitoring (TDM) research on anticancer drugs, analyze research hotspots and trends, and provide insights and references for future studies.MethodsData were retrieved from the Web of Science Core
Can Qian   +9 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Unveiling the complex networks of urban tree diversity research: A global perspective

open access: yesEcology and Evolution
Ecosystem services offered by urban forests must be proactively managed to remain diverse and sustainable. Recent research findings deserve a systematic synthesis to elucidate inherent knowledge structures and dynamics.
Chunping Xie   +3 more
doaj   +1 more source

Analysis and Prospect of Soil Organic Carbon Research Process in Recent 30 Years at Home and Abroa

open access: yesShuitu baochi yanjiu, 2020
Citespace bibliometrics software was used to sort out the literature regarding soil organic science in Web of Science and CNKI. By analyzing the frequency, centrality and clustering of keywords, and mutation words, we clarify the development of soil ...
ZHOU Mi   +6 more
doaj  

Hotspots and Development Trends in Global Mathematics Education Research on a Quantitative Analysis Utilizing the Cite Space Knowledge Map

open access: yesJournal of Social Sciences and Economics, 2023
Utilizing the literature from the Web of Science Core Collection database spanning the years 2013-2023 as a sample, this study employs the bibliometric tool CiteSpace to analyze publication quantity, countries, research institutions, journals, and ...
Lei Li, Yu Tang
doaj   +1 more source

Manifesto for medical research [PDF]

open access: yes, 2015
The MRCG want to ensure there is a dynamic medical research environment in Ireland. Ensuring priority investment for medical research will help to deliver patient care, public health service transformation and economic and enterprise development.
Medical Research Charities Group
core  

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

Bibliometric analysis of racket sport-related injuries: global research landscape, hotspots, and trends

open access: yesFrontiers in Sports and Active Living
ObjectiveThis study aims to provide a comprehensive overview of racket sport-related injury research, focusing on research progress, collaboration networks, hotspots, and thematic evolution.
Zongyu Liu, George Liu, Chunying Li
doaj   +1 more source

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