Results 31 to 40 of about 106,644 (264)
Global Flood Disaster Research Graph Analysis Based on Literature Mining
Applied Sciences, 2022 Floods are the most frequent and highest-impact among the natural disasters caused by global climate change. A large number of flood disaster knowledge were buried in the scientific literature.
Min Zhang, Juanle Wang
doaj +1 more source
Frontiers in Plant ScienceSweetpotato is an economically important crop, and it has various advantages over other crops in addressing global food security and climate change.
Xiaoqing Meng +3 more
doaj +1 more source
Visualization Analysis of Construction Robots Based on Knowledge Graph
BuildingsConstruction robots are pivotal in advancing the construction industry towards intelligent upgrades. To further explore the current research landscape in this domain, the CNKI Chinese database and the Web of Science core database were employed as data ...
Runrun Dong, Cuixia Chen, Zihan Wang
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Research hotspots and future trends of hot corrosion research: a bibliometric analysis
RSC Advances, 2023 Knowledge map of hot corrosion research: six research hotspots of the hot corrosion research field were elucidated.
Andrieanto Nurrochman +4 more
openaire +2 more sources
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Frontiers in AgingObjectiveTo employ bibliometrics to identify the research hotspots and development trends of the intrinsic capacity of older people, thereby providing novel insights for future studies on the management of intrinsic capacity in older adults and further ...
Minhua Ren +5 more
doaj +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source