Results 161 to 170 of about 107,666 (263)

Bypassing Heteronuclear MRI: Metal‐Free Organosilicon Nanotracers for Background‐Free Hotspot 1H Imaging on Clinical Hardware

Advanced Science, EarlyView.
Organosilicon micelles enable background‐free molecular magnetic resonance imaging (MRI) while remaining fully compatible with standard proton (1H) hardware. By exploiting a spectrally silent 1H window at ∼0 ppm, the silicone nanotracer allows hotspot detection by 1H chemical‐shift imaging (CSI) without metals or heteronuclei, enabling direct overlay ...
Martin Orsagh, Dominik Havlicek, Andrea Galisova, Ondrej Sedlacek, Daniel Jirak   +4 more
wiley   +1 more source

A high-density SNP linkage map reveals a major LG3 QTL hotspot controlling early-maturity-related traits in ridge gourd (<i>Luffa acutangula</i>). [PDF]

Front Plant Sci
Chen Q, Guo Y, Li Y, Zhang L, Song H, Zeng Z, Su G, Deng J, Sun X, He X, Kang D, Chen Z.   +11 more
europepmc   +1 more source

Conditionally Significant eQTL and TWAS Analyses Identify MsRD26 as a Major Candidate Positive Regulator of Salt Tolerance in Medicago sativa L

Advanced Science, EarlyView.
Salt stress significantly impacts plant growth. Through population transcriptome, eQTL and TWAS analyses, we identified several candidate genes potentially associated with salt stress response. Functional assays suggested that some of these genes may contribute to salt tolerance.
Lin Chen, Yuqi Zhang, Xinyue Ma, Jinpeng Bi, Fei He, Li Zhao, Haiyue Lei, Zhengqin Xiao, Xue Wang, Tiejun Zhang, Ruicai Long, Junmei Kang, Qingchuan Yang   +12 more
wiley   +1 more source

Clinicopathological characterization of cervical squamous cell carcinoma with <i>PIK3CA</i> hotspot mutation: A single-institution study. [PDF]

Oncol Lett
Murray J, Kaur H, Smith C, Wu AA, Wu LS, Tsai YC, Hung CF, Wu TC, Xing D.   +8 more
europepmc   +1 more source

Electropulse‐Driven Dislocation Evolution in Sub‐10 nm Metallic Nanocrystals

Advanced Science, EarlyView.
Atomic‐scale TEM imaging reveals how nanosecond electropulses drive dislocation evolution in sub‐10 nm metallic nanocrystals. Enhanced electron scattering at structural heterogeneities nucleates dislocation loops and dipoles, which then repeatedly interact and annihilate, causing dislocation density fluctuations or structural disordering.
Youran Hong, Xiaoyu Zhai, Xing Li, Xinfang Zhang, Kexing Song, Ze Zhang, Jiangwei Wang   +6 more
wiley   +1 more source

Spatiotemporal Trend and Hotspot Analysis of Stillbirth Prevalence in Ghana. [PDF]

Health Sci Rep
Boateng C, Ofori MA, Mintah S, Acheampong EA, Swati BB, Boateng ID, Mohammed A.   +6 more
europepmc   +1 more source

Computationally Evidence‐Grounded Sequence‐First Design of Peptide Binders

Advanced Science, EarlyView.
BOND‐PEP enables controllable, sequence‐first peptide binder design by grounding generation in binding evidence retrieved for each target. It uses topology‐conditioned message passing to integrate relevant peptide examples with the target protein sequence, forming a residue‐level representation that guides the generation of diverse, target‐specific ...
Wenze Ding
wiley   +1 more source

Conservation status of ethnic minority medicinal plants in China for the thirty by thirty target. [PDF]

iScience
Han B, Gao J, Xia C, Yao R, Zhang X, Huang Y, Peng Y, Xue T, Luo C, Bussmann RW, Qi Y, Yu S.   +11 more
europepmc   +1 more source

TRPC3‐Driven Calcium Microdomains Instruct Peripheral Nerve Regeneration With Protective Implications for Central Neurons

Advanced Science, EarlyView.
How localized Ca2+ signals orchestrate neural repair remains unclear. Here, we show that TRPC3‐driven calcium microdomains direct nerve repair by coupling spatially confined Ca2+ signals to axon regeneration. This module operates in injured peripheral neurons and correlates with neuroprotection in Parkinson's disease, revealing a spatial logic for ...
Yu Lu, Jianbo Zhao, Zhenli Xie, Yuan Wang, Ruolin Wang, Bianbian Wang, Chuhan Shen, Yali Chen, Jingyu Yao, Ziyang Li, Huadong Xu, Zuying Chai, Zhuoyu Zhang, Changhe Wang, Rong Huang   +14 more
wiley   +1 more source

Integrative analytical and statistical framework for optimization of multiplex qPCR detection of <i>TGFBI</i> mutations in refractive surgery candidates. [PDF]

J Zhejiang Univ Sci B
Gu Y, Mao L, Li X, Sun K, Jiang Q, Wu W, Shen Y, Chen S, Zheng M, Xu Y.   +9 more
europepmc   +1 more source