Results 251 to 260 of about 51,114,329 (304)

Disentangling Heterogeneous Molecular Networks for Multi‐Omics‐Driven Cancer Driver Discovery

open access: yesAdvanced Science, EarlyView.
DRIVE integrates PPI topology and pan‐cancer multi‐omics profiles through dual‐view graph disentanglement, contrastive representation learning, and joint optimization. Across six PPI networks, DRIVE outperforms ten baselines and remains robust to structural and annotation perturbations.
Xinjing Gong   +8 more
wiley   +1 more source

AI‐Designed TREM1‐Targeted LYTAC Nanoparticles Reprogram the Neuroimmune Microenvironment in Traumatic Brain Injury

open access: yesAdvanced Science, EarlyView.
AI‐enabled de novo design of a TREM1 binder, integrated into a BBB‐crossing and macrophage‐targeted nanoplatform, enables TREM1 degradation and attenuates neuroinflammation, thereby promoting neuroprotection and tissue repair after traumatic brain injury. ABSTRACT Secondary neuroinflammation drives progressive damage after traumatic brain injury (TBI),
Yimin Huang   +19 more
wiley   +1 more source

Strategic Template Filtering Accelerates Fragment-Based Peptide Docking. [PDF]

open access: yesJ Chem Inf Model
Trabelsi-Mescheloff N   +4 more
europepmc   +1 more source

A conserved small RNA-generating gene cluster undergoes sequence diversification and contributes to plant immunity. [PDF]

open access: yesNat Commun
Feng L   +11 more
europepmc   +1 more source

Overcoming the last mile: practical strategies for leprosy elimination in Pakistan. [PDF]

open access: yesBMJ Glob Health
Fastenau A   +8 more
europepmc   +1 more source

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