Results 211 to 220 of about 6,818,964 (313)

Beyond the Publication-Equivalent: Rethinking research impact metrics. [PDF]

Indian J Med Res
Ghotankar SS, Juvekar SK.
europepmc   +1 more source

Retrospective Impact Evaluation Continuing to Prove Challenging Irrespective of Setting: A Study of Research Impact Enablers and Challenges Cloaked as an Impact Evaluation? Comment on "'We're Not Providing the Best Care If We Are Not on the Cutting Edge of Research': A Research Impact Evaluation at a Regional Australian Hospital and Health Service". [PDF]

Int J Health Policy Manag, 2023
Ramanathan S.
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Optimizing Research Impact: A Toolkit for Stakeholder-Driven Prioritization of Systematic Review Topics. [PDF]

Cochrane Evid Synth Methods
Hoekstra D, Lhachimi SK.
europepmc   +1 more source

Evaluating cancer research impact: lessons and examples from existing reviews on approaches to research impact assessment. [PDF]

Health Res Policy Syst, 2021
Hanna CR, Boyd KA, Jones RJ.
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Associations Between Nursing Faculty Expertise in the United Nations Sustainable Development Goals and Research Impact Metrics: A Cross-Sectional Study. [PDF]

J Nurs Manag
Ruksakulpiwat S, Thongking W, Niyomyart A, Benjasirisan C, Phianhasin L, Kongkar R, Praha N, Adams J, El-Osta A.   +8 more
europepmc   +1 more source

Development of a framework and research impact capture tool for nursing, midwifery, allied health professions, healthcare science, pharmacy and psychology (NMAHPPs). [PDF]

BMC Health Serv Res, 2023
Newington L, Wells M, Begum S, Lavender AJ, Markham S, Tracy O, Alexander CM.   +6 more
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Research impact assessment of a Canadian digital health funding program: a case study. [PDF]

Health Res Policy Syst
Nadigel J, Kasaai B, Thorsteinsdóttir H, Rogers S, McMahon M, Rylett RJ, Glazier RH.   +6 more
europepmc   +1 more source