Results 31 to 40 of about 50,249,813 (232)

Tools and Ontologies for the Aggregation and Management of Cypriot Archaeological Datasets

open access: yesInternet Archaeology, 2023
This article focuses on the aggregation of Cypriot archaeological datasets, digitally archived in local repositories, into the ARIADNE portal. It considers, in particular, the development of an application profile for inscriptions and presents the ...
Valentina Vassallo   +3 more
doaj   +1 more source

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye   +33 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Supporting executable scientific workflows in a clustered Infrastructure: DARIAH-IT and H2IOSC [PDF]

open access: yesTransformations
Workflows have become essential in digital humanities, enabling the formalisation, automation and reproducibility of complex research processes. As the humanities increasingly adopt data-driven methodologies, workflows offer structured approaches to ...
Emiliano Degl'Innocenti   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Towards a feasible and representative pan-African research infrastructure network for GHG observations

open access: yesEnvironmental Research Letters, 2018
There is currently a lack of representative, systematic and harmonised greenhouse gas (GHG) observations covering the variety of natural and human-altered biomes that occur in Africa. This impedes the long-term assessment of the drivers of climate change,
Ana López-Ballesteros   +19 more
doaj   +1 more source

In Between Research Cultures – The State of Digital Humanities in Finland

open access: yesInformaatiotutkimus, 2018
Digital humanities (DH) as a research field has been developing rapidly in Finland during the past few years, mainly due to increased funding and profiling activities. Although these infrastructural developments have created (smaller and larger) centres,
Inés Matres, Mila Oiva, Mikko Tolonen
doaj   +1 more source

In Situ Pavement Monitoring: A Review

open access: yesInfrastructures, 2020
The assessment of pavement conditions and their evolution with time is a crucial component for the establishment of pavement quality management (QM) plans and the implementation of QM practices.
Maria Barriera   +3 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Learning-in-Games Approach for the Mission Planning of Autonomous Multi-Drone Spatio-Temporal Sensing

open access: yesIEEE Access
Mission planners are one of the major classes of autonomy software and their design is especially challenging in the case cooperation autonomy is required for unmanned multi-vehicle systems.
Vittorio U. Castrillo   +4 more
doaj   +1 more source

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