Results 101 to 110 of about 1,495,900 (311)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Commentary on "targeting versus instrument rules for monetary policy: what is wrong with McCallum and Nelson?" [PDF]

The following are comments in response to Lars Svensson's "Targeting versus Instrument Rules for Monetary Policy: What Is Wrong with McCallum and Nelson?"Monetary ...
Bennett T. McCallum, Edward Nelson
core  

Effects of Supplemental Effective Microorganisms in Feed on the Growth, Lipid Deposition and GH–IGF-I Axis of the Blunt Snout Bream Megalobrama amblycephala

Aquaculture Nutrition
The aim of this study was to investigate the effects of an effective microorganism (EM)-based microbial inoculum on the growth and expression of related genes in 1-year-old healthy Megalobrama amblycephala.
Hao Zhu, Fan Wu, Xuan Che, Jinxing Xiao
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Technology and skill: dividing engines in the Nineteenth Century

, 2008
Recent studies in the making of scientific knowledge have demonstrated that science and technology are mutually dependant on each other. One example here is the manufacture of scientific instruments.
Staubermann, Klaus
core  

Mystery shopping as an instrument of marketing research [PDF]

, 2007
Článek pojednává o metodě marketingového výzkumu zvané mystery shopping. Mystery shopping je výzkumná metoda, jejíž princip vychází z tzv. utajeného nákupu, pomocí kterého je zjišťována úroveň prodeje a připravenost jednotlivých prodejních míst nebo ...
Staňková, Pavla, Vaculíková, Marcela
core  

Ways of knowing, ways of writing: technical practice research in new musical instrument design [PDF]

Musical instruments are not static and neutral technological objects, but objects we shape through our designing and performing practices. Along these lines, various authors have argued for the relevance of practice research in the New Interfaces for ...
Mcpherson, A, Fiebrink, R, Pelinski Ramos, T   +2 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Automated vision occlusion-timing instrument for perception–action research

, 2017
Vision occlusion spectacles are a highly valuable instrument for visual-perception–action research in a variety of disciplines. In sports, occlusion spectacles have enabled invaluable knowledge to be obtained about the superior capability of experts to ...
Sean Müller, Müller, S., Robbie Rhodes, Brad Finch, Brenton, John, Finch, Brad, Brenton, J., John Brenton, Müller, Sean, Finch, B., Rhodes, Robbie, Rhodes, R.   +11 more
core   +1 more source