Results 101 to 110 of about 4,143,589 (309)

GREAT: the SOFIA high-frequency heterodyne instrument

, 2012
We describe the design and construction of GREAT, the German REceiver for Astronomy at Terahertz frequencies operated on the Stratospheric Observatory for Infrared Astronomy (SOFIA).
Becklin, de Graauw, Guan, H. W. Hübers, Horn, J. Stutzki, Klein, Klein, P. Hartogh, Pilbratt, Pütz, R. Güsten, Röser, S. Heyminck, U. U. Graf, Villanueva, Wagner-Gentner, Young   +17 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

The Goldstone solar system radar: A science instrument for planetary research [PDF]

The Goldstone Solar System Radar (GSSR) station at NASA's Deep Space Communications Complex in California's Mojave Desert is described. A short chronological account of the GSSR's technical development and scientific discoveries is given.
Dvorsky, J. D., Fulton, D. E., Renzetti, N. A.   +2 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Effects of Supplemental Effective Microorganisms in Feed on the Growth, Lipid Deposition and GH–IGF-I Axis of the Blunt Snout Bream Megalobrama amblycephala

Aquaculture Nutrition
The aim of this study was to investigate the effects of an effective microorganism (EM)-based microbial inoculum on the growth and expression of related genes in 1-year-old healthy Megalobrama amblycephala.
Hao Zhu, Fan Wu, Xuan Che, Jinxing Xiao
doaj   +1 more source

The Wide Field Spectrograph (WiFeS): Performance and Data Reduction

, 2010
This paper describes the on-telescope performance of the Wide Field Spectrograph (WiFeS). The design characteristics of this instrument, at the Research School of Astronomy and Astrophysics (RSAA) of the Australian National University (ANU) and mounted ...
Bloxham, Gabe, Busarello, Gianni, Dopita, Michael, Farage, Catherine, Firth, Peter, Green, Anthony, McGregor, Peter, Merluzzi, Paola, Neilson, Jon, Rhee, Jonghwan, Roberts, Bill, Wilson, Greg, Young, Peter   +12 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Transmission Oscillator Ultrasonic Spectrometer (TOUS): A new research instrument [PDF]

, 1975
TOUS is capable for measuring very small changes in acoustic attenuation and phase velocity. Its high sensitivity to small changes in ultrasonic absorption results in part from operation under marginal conditions.
Conradi, M. S., Heyman, J. S., Miller, J. G., Stone, F. D.   +3 more
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source