Results 131 to 140 of about 1,495,900 (311)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Abatement Cost Uncertainty and Policy Instrument Selection under a Stringent Climate Policy. A Dynamic Analysis [PDF]

This paper investigates the relative economic and environmental outcomes of price versus quantity mechanisms to control GHG emissions when abatement costs are uncertain. In particular, we evaluate the impacts on policy costs, CO2 emissions and energy R&D
Alexander Golub, Valentina Bosetti, Massimo Tavoni, Emanuele Massetti   +3 more
core  

Knowledge-GAP Survey Instrument

, 2023
This is the main research instrument for the NSF funded BCSER-IID: Undergraduate Knowledge of the Mathematics Graduate School Application Process (Knowledge-GAP) project.
McEldowney, Tim, Deshler, Jessica, Michaluk, Lynnette   +2 more
core  

Mechanisms of the Effect of Starvation Duration on the Regulation of Feeding Rhythm and Metabolic Physiology of Cultured Large Yellow Croaker (Larimichthys crocea)

Journal of Marine Science and Engineering
In recent years, significant progress has been made in China in the field of deep-sea large yellow croaker (Larimichthys crocea) farming. Compared with the traditional inshore aquaculture model, deep-sea culture of large yellow croaker enjoys a wider ...
Xiaomeng Wang, Huang Liu, Chenglin Zhang, Chen Zhu, Huiyi Liu   +4 more
doaj   +1 more source

Adaptation of a nursing home culture change research instrument for frontline staff quality improvement use. [PDF]

Psychol Serv, 2017
Hartmann CW, Palmer JA, Mills WL, Pimentel CB, Allen RS, Wewiorski NJ, Dillon KR, Snow AL.   +7 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Electro-ocular Measurement and Control Technique by Integrating Virtual Instrument

, 2012
[[abstract]]In this research, electro-ocular control technique is designed and constructed. The structure of virtual instrument built by software part, LabviewBhardware part, DAQ card and some external circuits is applied in the development process. This
Yao, Kai-chao; Huang, Wei-tzer
core  

Research Experiences Instrument Scoring Guide

, 2021
This document is a scoring guide to assist higher-education administrators, faculty, and researchers who wish to use the Research Experiences Instrument (REI).
Holloway, Eric, Oakes, William Charles, Radcliffe, David, Douglas, Kerrie Anna   +3 more
core  

The Soft X-ray Research instrument at the Linac Coherent Light Source. [PDF]

J Synchrotron Radiat, 2015
Dakovski GL, Heimann P, Holmes M, Krupin O, Minitti MP, Mitra A, Moeller S, Rowen M, Schlotter WF, Turner JJ.   +9 more
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source