Results 31 to 40 of about 23,925,489 (332)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

How to Write an English Research Introduction?

Ethical Lingua: Journal of Language Teaching and Literature, 2017
This study is librarian analysis which collects the data from books and journal articles. Those articles and books chapters discuss about introductions in terms of their generic structures.
Warsidi Warsidi
doaj   +3 more sources

Book phenomenon in library philosophy and library research

Knygotyra
The book plays the most important role in the development of the culture of our civilization—the mental heritage of all generations for all generations is contained in books. The most important feature of the book is that it serves as a knowledge keeper
Baiba Sporane
doaj   +3 more sources

Conversational AI Chatbots in library research: An integrative review and future research agenda

Journal of Library and Information Sciences
The growing role of conversational AI Chatbots continues to change the library and information service landscape. Chatbots are replacing some of the library services that humans conventionally perform.
M. Aboelmaged, Shaker Bani‐Melhem, Mohd Ahmad Al-Hawari, Ifzal Ahmad   +3 more
semanticscholar   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Research Forum: Creating and Sustaining an Intra-library Venue to Share Library Faculty Research

Journal of Librarianship and Scholarly Communication, 2020
INTRODUCTION Research and evidence-based practices are vital to library work, but we are often unaware of the research conducted by colleagues within our own institutions.
Emily D Spunaugle, Joanna Thielen, Stephanie Swanberg   +2 more
doaj   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Knjižnica centra za istraživanje mora [PDF]

Kemija u Industriji, 2005
Library of the Centre for marine research in Rovinj, Ruđer Bošković ...
Erman, Danijela
doaj  

Promoting a Rapid Deployment of New Services for Remote Reference at a National Laboratory [PDF]

Marketing Libraries Journal, 2021
Libraries around the world use Springshare library products to expand their reference and information literacy services. The scholarly literature primarily addresses the use of Springshare’s LibGuides and LibChat in academic libraries.
Moyer, Elizabeth , Hayes,Sarah Lynn , Mittrach, Michelle Aileen   +2 more
doaj  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source