Results 121 to 130 of about 9,180,898 (317)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Analysing multimodal data that have been collected using photovoice as a research method. [PDF]

BMJ Open, 2023
Mooney R, Bhui K, Co-Pact Project Team.
europepmc   +1 more source

Analytic density, postmodernism, and applied multiple method research

, 2017
The developmental trajectory of multiple method research is a somewhat curious one. Combining methods is at least as old as Thucydides’ account of the Peloponnesian wars, in which the speeches constituting a quarter of the History offer insight into the ...
Fielding, NG
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Theme-centered interaction and developmental tasks as research method and pedagogical tool regarding identity development in VET. [PDF]

Front Psychol, 2023
Thole C.
europepmc   +1 more source

Prioritising research and dissemination: a Delphi study of NHS Highland midwives [PDF]

, 2012
 This paper reports on a Delphi study undertaken by a health librarian and two midwifery professionals, to determine the research priorities of midwives working in NHS Highland. Six important topics were identified: workforce issues, second stage of
Felce, Alison, Irvine, Kathleen, Jessiman, Wendy C   +2 more
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Hydroxysafflor Yellow A Reduced Neuroinflammation Induced by Astrocyte-Derived IL-17A by Inhibiting the IL-17RA/ACT1/NF-κB/IL-17A Loop After OGD/R

Journal of Inflammation Research
Lijuan Song,1,2,* Jianlin Hua,2,3,* Kexin Liu,2 Yanzhe Duan,2 Yukang Sun,2 Jiezhong Yu,1,4 Jinzhu Yin,2,3,5 Cungen Ma,1,2 Baoguo Xiao,2,6 Dong Ma,2,3,5 Jianjun Huang2– 4 1Shanxi Key Laboratory of Innovative Drug for the Treatment of ...
Song L, Hua J, Liu K, Duan Y, Sun Y, Yu J, Yin J, Ma C, Xiao B, Ma D, Huang J   +10 more
doaj  

The Effects of Virtual Reality Telemedicine With Pediatric Patients Diagnosed With Posttraumatic Stress Disorder: Exploratory Research Method Case Report. [PDF]

JMIR Form Res, 2023
Bogdanski E.
europepmc   +1 more source

Research Methods: Sampling

Evidence Based Library and Information Practice, 2014
No abstract.
openaire   +6 more sources