Results 181 to 190 of about 9,180,898 (317)

Experimental investigation of an interior search method within a simple framework

open access: yes, 1986
A steepest gradient method for solving Linear Programming (LP) problems, followed by a procedure for purifying a non-basic solution to an improved extreme point solution have been embedded within an otherwise simplex based optimiser.
Mitra, G, Yadeger, J, Tamiz, M
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

A Review of Authors Research Methods of Articles in the Journal of Hospital over the Past Two Years Running Title: Hospital journal Research Methodology

open access: yesبیمارستان, 2019
Background: One of the most important ways to promote the quality and attractiveness of the journal for readers is the accurate evaluation of the published articles research methodology in the journals.
Abbas Jahangiri, Mohammad Jahangiri
doaj  

Delphi Method and Nominal Group Techniques in Family Planning and Reproductive Health Research

open access: yes, 2006
Both the Delphi method and nominal group technique offer structured, transparent and replicable ways of synthesising individual judgements and have been used extensively for priority setting and guideline development in health-related research including ...
Edwin van Teijlingen (64309)   +7 more
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

ODOT research news. [PDF]

open access: yes
The ODOT Research News includes: 1) The 2006 Northwest Transportation Conference will be held February 7-9, at the Oregon State University. 2) The annual project solicitation for ODOT\u2019s research program is underway.
Oregon. Dept. of Transportation. Research Unit
core   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Bridging laboratory and field research: Method adjustments to blood feed field-derived Aedes aegypti. [PDF]

open access: yesPLoS Negl Trop Dis
Epelboin Y   +6 more
europepmc   +1 more source

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