Results 241 to 250 of about 9,180,898 (317)
Quantitative comparison of cranial approaches in the anatomy laboratory: A neuronavigation based research method. [PDF]
World J Methodol, 2017 Doglietto F +9 more
europepmc +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
A scoping review of the potential for chart stimulated recall as a clinical research method. [PDF]
BMC Health Serv Res, 2017 Sinnott C, Kelly MA, Bradley CP.
europepmc +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Experience and Utility of Using the Participatory Research Method, Photovoice, in Individuals With Spinal Cord Injury. [PDF]
Top Spinal Cord Inj Rehabil, 2018 LaVela SL, Balbale S, Hill JN.
europepmc +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Mental health facility codesign: A new research method for integrating the service user voice in design processes using virtual reality. [PDF]
Gen Psychiatr, 2019 Liddicoat S.
europepmc +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
An Investigation of the Efficacy of Asynchronous Discussion on Students' Performance in an Online Research Method Course. [PDF]
Behav Anal Pract, 2018 Malkin A, Rehfeldt RA, Shayter AM.
europepmc +1 more source