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Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
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The Journal of the American Dental Association, 2016
This chapter presents the methodology of this study and the rationale for using qualitative interviewing as the preferred approach. It discusses the practicalities of the research methodology, including the processes of developing an interview framework, engaging participants and analysing research material using Grounded Theory.
Irene Zempi, Imran Awan
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This chapter presents the methodology of this study and the rationale for using qualitative interviewing as the preferred approach. It discusses the practicalities of the research methodology, including the processes of developing an interview framework, engaging participants and analysing research material using Grounded Theory.
Irene Zempi, Imran Awan
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2019
Abstract The authors present an overview of methodological issues in comparative studies, which have their intellectual roots in experimental psychology. This is followed by an introduction of the key concepts of bias (unintended sources of score differences, such as differential social desirability) and equivalence (implications of bias
He, Jia, van de Vijver, Fons
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Abstract The authors present an overview of methodological issues in comparative studies, which have their intellectual roots in experimental psychology. This is followed by an introduction of the key concepts of bias (unintended sources of score differences, such as differential social desirability) and equivalence (implications of bias
He, Jia, van de Vijver, Fons
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Nursing Standard, 2015
Mixed methods research involves the use of qualitative and quantitative data in a single research project. It represents an alternative methodological approach, combining qualitative and quantitative research approaches, which enables nurse researchers to explore complex phenomena in detail.
Halcomb, Elizabeth J, Hickman, Louise
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Mixed methods research involves the use of qualitative and quantitative data in a single research project. It represents an alternative methodological approach, combining qualitative and quantitative research approaches, which enables nurse researchers to explore complex phenomena in detail.
Halcomb, Elizabeth J, Hickman, Louise
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Methods of intersectional research
Sociological Spectrum, 2020Intersectionality is a powerful concept within sociology, urging scholars to consider how an array of socially constructed dimensions of difference intersect to shape each person’s experiences and ...
Joya Misra +2 more
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Photography as a Research Method
2014This chapter discusses the development of photography as a research method in social sciences. It describes the different types of photographs used, such as archival photographs and photographs taken by the researcher, and it focuses especially on photographs taken by participants.
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Proceedings of the 35th Annual Hawaii International Conference on System Sciences, 2003
In information systems (IS), the ethical conduct of research may be something which we take for granted, or perhaps simply ignore. Given the seriousness of ethical dilemmas that can arise, however; it is important to pay attention to ethical issues. A personal perspective is given on the nature of ethics in information systems research.
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In information systems (IS), the ethical conduct of research may be something which we take for granted, or perhaps simply ignore. Given the seriousness of ethical dilemmas that can arise, however; it is important to pay attention to ethical issues. A personal perspective is given on the nature of ethics in information systems research.
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Research Methods in Epidemiology
Neurologic Clinics, 2016Epidemiology is the study of the distribution and determinants of health-related states and in specified populations and the application to control health problems. Classified as either descriptive or analytical, a variety of epidemiologic approaches can be used to allow assessment of hypothesized risk factor exposure with disease outcomes.
David S, Younger, Xiaoling, Chen
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Statistical Methods in Research
2011Statistical methods appropriate in research are described with examples. Topics covered include the choice of appropriate averages and measures of dispersion to summarize data sets, and the choice of tests of significance, including t-tests and a one- and a two-way ANOVA plus post-tests for normally distributed (Gaussian) data and their non-parametric ...
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Anthropologischer Anzeiger, 2009
Mummies are human remains with preservation of non-bony tissue. Many mummy studies focus on the development and application of non-destructive methods for examining mummies, including radiography, CT-scanning with advanced 3-dimensional visualisations, and endoscopic techniques, as well as minimally-destructive chemical, physical and biological methods
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Mummies are human remains with preservation of non-bony tissue. Many mummy studies focus on the development and application of non-destructive methods for examining mummies, including radiography, CT-scanning with advanced 3-dimensional visualisations, and endoscopic techniques, as well as minimally-destructive chemical, physical and biological methods
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