In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Implementing Cultural Safety in Research Methodology: The Co-Design Process of a Brief Therapeutic Intervention for Aboriginal and Torres Strait Islander Young People Who Engage in Self-Harm and/or Suicidal Behaviours. [PDF]
D'Mello C +7 more
europepmc +1 more source
Commentary: Centering Oppression in Research Methodology Toward Developing Interventions to Address Health Inequities. [PDF]
Hacker N +3 more
europepmc +1 more source
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
Research Methodology in Acupuncture for Managing Interstitial Cystitis/Bladder Pain Syndrome: A Scoping Review. [PDF]
Infantes Rosales MÁ +3 more
europepmc +1 more source
Advancing qualitative rare disease research methodology: a comparison of virtual and in-person focus group formats. [PDF]
Dwyer AA, Uveges M, Dockray S, Smith N.
europepmc +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Redesigning online research methodology education: insights from undergraduate rehabilitation students' experiences in South Africa. [PDF]
Louw QA +4 more
europepmc +1 more source
Asset mapping score analysis: a novel public health research methodology applied to maternal and child health resources in New Orleans. [PDF]
Healy J, Ramirez S, Knapp M, Johnson C.
europepmc +1 more source

