Results 191 to 200 of about 26,805,984 (378)
Clinical research methodology process: what is changing with COVID-19? [PDF]
Eur Heart J Suppl, 2021 Tavazzi L.
europepmc +1 more source
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Inculcating research methodology related skills and aptitude amongst medical undergraduates- An interventional study. [PDF]
J Family Med Prim Care, 2022 Shukla S +4 more
europepmc +1 more source
Fratricide: defective decision making
, 2009 Motivation – to explore the applicability of a Human Factors methodology for the investigation of fratricide. Research approach – The EAST methodology was used to analyse an incident of fratricide and its ability to explore the Famous Five of Fratricide (
Rafferty, Laura A. +2 more
core
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Using Facebook Advertisements for Women's Health Research: Methodology and Outcomes of an Observational Study. [PDF]
JMIR Form Res, 2022 Farr DE, Battle DA, Hall MB.
europepmc +1 more source
Identifying prognostic targets in metastatic prostate cancer beyond AR
FEBS Open Bio, EarlyView.Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng +13 more
wiley +1 more source
Harmonizing epidemiological research methodology for atopic dermatitis research: protocol for the EPISTAR international consensus exercise. [PDF]
Skin Health DisKeddie SH +20 more
europepmc +1 more source