Results 141 to 150 of about 2,405,022 (374)

Critical social science as a research methodology in universities in times of crisis

Qualitative Research Journal, 2020
PurposeTo consider what a criticalist qualitative research methodology might look like for universities in the context of the contemporary COVID-19 crisis.Design/methodology/approachThis polemical paper explores the rationale for a dramatic recasting of the approach needed in qualitative research methodology to address the challenges of the crisis ...
openaire   +2 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

To Engage Research Critically : A Review of Kerry Howell ’s The Philosophy of Methodology [PDF]

, 2013
The turn to philosophical grounding in qualitative research demands a depth of historical and conceptual knowledge that many trained in the social sciences may lack.
Larkin, Allyson
core   +1 more source

Tumor‐agnostic detection of circulating tumor DNA in patients with advanced pancreatic cancer using targeted DNA methylation sequencing and cell‐free DNA fragmentomics

Molecular Oncology, EarlyView.
We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin, Kjersti Tjensvoll, Karin Hestnes Edland, Satu Oltedal, Herish Garresori, Bjørnar Gilje, Saga Ekedal, Trygve Eftestøl, Jan Terje Kvaløy, Filip Janku, Oddmund Nordgård   +10 more
wiley   +1 more source

Multiple Methods, Communicative Preferences and the Incremental Interview Approach Protocol

Forum: Qualitative Social Research, 2009
This article introduces a multiple methods data collection protocol. The protocol has been designed mainly for those unsure of the practical steps needed to insure coherent data-sets with respect to the substantive, theoretical and methodological issues ...
David M. Hoffman
doaj  

Communicating the interdependence of human, animal, and environmental health on X (formerly Twitter): Insights from the one health approach

iScience
Summary: The COVID-19 pandemic has underscored societies’ need for education and preparedness in addressing global environmental and health crises. Raising public awareness of the interdependence of human, animal, and environmental health is essential to
Juan M. Requena-Mullor, Enrica Garau, María D. López-Rodríguez, Cristina Quintas-Soriano, Antonio J. Castro Martínez   +4 more
doaj   +1 more source

Socially responsible design science in information systems for sustainable development: a critical research methodology [PDF]

, 2021
Mike Monson
openalex   +1 more source

Cultural representations of mental illness in contemporary Japan [PDF]

, 2014
This paper presents the results of a research project aimed at studying the cultural representations of mental illness and related interventions models in contemporary Japan, and providing the basis for a comparison between Japanese and Italian mental ...
Bucci, Fiorella
core  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Participatory Modeling: A Methodology for Engaging Stakeholder Knowledge and Participation in Social Science Research [PDF]

, 2022
Barbara Quimby, Melissa Beresford
openalex   +1 more source