Results 161 to 170 of about 1,735,729 (314)

Multiple Methods, Communicative Preferences and the Incremental Interview Approach Protocol

Forum: Qualitative Social Research, 2009
This article introduces a multiple methods data collection protocol. The protocol has been designed mainly for those unsure of the practical steps needed to insure coherent data-sets with respect to the substantive, theoretical and methodological issues ...
David M. Hoffman
doaj  

Do You See what I See? Tracking the Perceptual Beliefs of Robots

iScience, 2020
Summary: Keeping track of others' perceptual beliefs—what they perceive and know about the current situation—is imperative in many social contexts. In a series of experiments, we set out to investigate people's ability to keep track of what robots know ...
Sam Thellman, Tom Ziemke
doaj  

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Carrying out research across the arts and humanities and social sciences: developing the methodology for Dementia and Imagination [PDF]

, 2016
Andrew Newman, Michael Baber, Dave O’Brien, Anna Goulding, Jones Ch, Teri Howson-Griffiths, Carys Jones, Clive Parkinson, Katherine Taylor, Victoria Tischler, Gill Windle   +10 more
openalex   +1 more source

Germline variants in CDKN2A wild‐type melanoma prone families

Molecular Oncology, EarlyView.
Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen, Marie Loeng, Amalie Lund Holth, Per E. Lønning, Jürgen Geisler, Stian Knappskog   +5 more
wiley   +1 more source

Observational studies of exposure to tobacco and nicotine products: Best practices for maximizing statistical precision and accuracy

iScience
Summary: Non-randomized observational studies can track risk-induction and -reduction associated with real-world use of non-combusted nicotine and tobacco products.
Gal Cohen, Steven Cook
doaj  

Decoding Digital Influence: The Role of Social Media Behavior in Scientific Stratification Through Logistic Attribution Method [PDF]

arXiv
Scientific social stratification is a classic theme in the sociology of science. The deep integration of social media has bridged the gap between scientometrics and sociology of science. This study comprehensively analyzes the impact of social media on scientific stratification and mobility, delving into the complex interplay between academic status ...
arxiv  

Cultural representations of mental illness in contemporary Japan [PDF]

, 2014
This paper presents the results of a research project aimed at studying the cultural representations of mental illness and related interventions models in contemporary Japan, and providing the basis for a comparison between Japanese and Italian mental ...
Bucci, Fiorella
core  

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source