Results 171 to 180 of about 2,566,888 (342)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Dropout rates and factors associated with adherence to opioid agonist treatment among adults with opioid use disorder at Sekou Toure Regional Referral Hospital, Mwanza, Tanzania. [PDF]

Front Psychiatry
Tuli TH, Rweyendera A, Gwahula G, Vedastus Y, Maziku R, Chilipweli P, Hauli KA.   +6 more
europepmc   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Study Protocol: Connecting older adults through multi-level programmes for alleviating loneliness in Hong Kong older adults (COMPASS-HOA). [PDF]

Front Public Health
Tang VFY, Jiang D, Kwok JYY, Ho HCY, Jian IY, Choi NG, Cruwys T, You JHS, Warner LM, Seewer N, Bai X, Käll A, Andersson G, Krieger T, Lloyd-Evans B, Chou KL.   +15 more
europepmc   +1 more source

Forecasting a Language Shift Based on Cellular Automata [PDF]

Language extinction as a consequence of language shifts is a widespread social phenomenon that affects several million people all over the world today.
Doris Ferreres, Francesc S. Beltran, Marc-Antoni Adell, Marcos Ruiz-Soler, Salvador Herrando, Violant Estreder   +5 more
core  

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Teaching cornerball: a didactic proposal based on the sport education model. [PDF]

Front Sports Act Living
Diez-Fernández P, Rodríguez-Cayetano A, Gutiérrez-Gutiérrez S, Barcala-Furelos M, González-Gutiérrez I, Ruibal-Lista B, López-García S.   +6 more
europepmc   +1 more source

Consultation on methodological research needs in UK Social Science

, 2015
As part of its national strategic remit, NCRM undertakes periodic assessments of national provision and need in methodological research and training through consultation with stakeholders. In November of 2014 NCRM carried out a third consultation on the views of the UK social science research community about current and future methodological research ...
Luff, Rebekah, Wiles, Rose, Sturgis, Patrick   +2 more
openaire   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source