Results 21 to 30 of about 355,754 (301)

Research traditions in social sciences and their methodological rationales

open access: yesAloma: Revista de Psicologia, Ciències de l'Educació i de l'Esport, 2018
The aim of this article is to review and describe the most common research paradigms in social sciences in order to then use this knowledge to inform the choice of research methods. Paradigms are defined here as traditions generated by the diversity of ways of understanding reality and the associated beliefs about what knowledge is and how it can be ...
openaire   +5 more sources

Scope and financial impact of unpublished data and unused samples among U.S. academic and government researchers

open access: yesiScience, 2023
Summary: Unpublished data and unused samples are common byproducts of research activity, but little is known about the scope and economic impact of their disuse.
Emma C. Bowers   +3 more
doaj  

The unpredictably eruptive dynamics of spruce budworm populations in eastern Canada

open access: yesPopulation Ecology, EarlyView.
We examine historical population data for spruce budworm from several locations through the period 1930–1997, and use density‐dependent recruitment curves to test whether the pattern of population growth over time is more consistent with Royama's (1984; Ecological Monographs 54:429–462) linear R(t) model of harmonic oscillation at Green River New ...
Barry J. Cooke, Jacques Régnière
wiley   +1 more source

Development and expansion in the marine social sciences: Insights from the global community

open access: yesiScience, 2022
Summary: The importance of understanding the complexities of societal relationships with our global ocean, and how these influence sustainable management and effective, equitable governance, is crucial to addressing ocean challenges.
Emma McKinley   +5 more
doaj  

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

Conceptual and Methodological Research of Xenophobia in Social Sciences

open access: yesMediterranean Journal of Social Sciences, 2015
The article presents a conceptual and methodological analysis of xenophobia study in social sciences. In order to investigate the phenomenon of xenophobia, the authors propose to use the methodology of constructive realism that makes it possible to substantiate the social nature of criteria for defining the "outsiders" and their dynamics.
A. Popov   +4 more
openaire   +3 more sources

Gender and choice of methodology in tourism social science research [PDF]

open access: yesAnnals of Tourism Research, 2017
•We analyzed gender and choice of methodology.•Male authors constituted more than 65% of all authors.•Linear effect indicated that time explained growth of male and female authors.•Quadratic effect indicated acceleration in female authorship.•Women researchers have a preference for qualitative research methods.
Nunkoo, Robin   +2 more
openaire   +3 more sources

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

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