Results 111 to 120 of about 52,837,615 (296)

The 23rd Annual Boston University Undergraduate Research (UROP) Abstracts, Summer 2020 [PDF]

, 2020
This file is available for the BU community only. Downloading this file for public distribution is strictly prohibited. BU Community members may access the file via Kerberos password login.This UROP Symposium booklet includes all abstracts from students ...
The Undergraduate Research Opportunities Program, Boston University
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Integrative Physiology: Update to the Grand Challenge 2020

Frontiers in Physiology, 2020
Geoffrey A. Head
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Saturation in the digital qualitative research: examining the factors influencing saturation attainment

Cogent Arts & Humanities
Qualitative research is considered a fundamental tool for investigating complex phenomena and for seeking answers as well as gaining in-depth insights of lived experiences of people. A critical aspect of qualitative research is the concept of saturation,
Favourate Y. Mpofu, Samantha Lufuno Mudau   +1 more
doaj   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Report on the appropriateness of the Scottish Councils job evaluation scheme in relation to classroom assistants [PDF]

, 2007
This report was commissioned by the Equal Opportunities Commission (Scotland) as part of the General Formal Investigation into the status and pay of classroom assistants in Scotland.
Gilbert, K., , Equal Opportunities Commission (Funder), Equal Opportunities Commission (Funder)   +2 more
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UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Recommendations on intellectual property and knowledge transfer for charity-funded research [PDF]

, 2018
A core belief of the HRCI is that charity-funded research should be used for public good; for the benefit of patients and to improve the nation’s health.
Medical Research Charities Group
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