Results 151 to 160 of about 8,443,323 (284)

Large language model-assisted research question development in public health: a case study in the Special Supplemental Nutrition Program for Women, Infants, and Children. [PDF]

Public Health Nutr
Zhang Q, Neupane B, Patel P, Alkhalifah FN, He Y, Hodges L.   +5 more
europepmc   +1 more source

The Research Question

, 2016
La pregunta de investigación es el aspecto medular en una investigación. Su planteamiento es producto de la idea de investigación, profundización en la teoría del fenómeno de interés, revisión de estudios previos, entrevistas con expertos, entre otras.
openaire   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Reply to: Statins in esophageal variceal bleeding: The right data for the right research question. [PDF]

Hepatol Commun
Kimer N, Gantzel RH, Kronborg TM.
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

All I want for Christmas…is a precisely defined research question. [PDF]

Trials
Cro S, Phillips R.
europepmc   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Unveiling the power of language models in chemical research question answering. [PDF]

Commun Chem
Chen X, Wang T, Guo T, Guo K, Zhou J, Li H, Song Z, Gao X, Zhang X.   +8 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

The fundamentals of eye tracking part 2: From research question to operationalization. [PDF]

Behav Res Methods
Hooge ITC, Nuthmann A, Nyström M, Niehorster DC, Holleman GA, Andersson R, Hessels RS.   +6 more
europepmc   +1 more source