Results 191 to 200 of about 2,932,079 (230)

MODOMICS: a database of RNA modifications and related information. 2025 update and 20th anniversary. [PDF]

Nucleic Acids Res
Sordyl D, Boileau E, Bernat A, Maiti S, Mukherjee S, Moafinejad SN, Farsani MA, Shavina A, Cappannini A, Agostini G, Conticello SG, Stefaniak F, Dieterich C, Purta E, Bujnicki JM.   +14 more
europepmc   +1 more source

Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer, Frauke Stascheit, Maximilian Mönch, Paolo Doksani, Carla Dusemund, Meret Herdick, Philipp Mergenthaler, Maike Stein, Amani Suboh, Jutta Schröder‐Braunstein, Guido Wabnitz, Jan D. Lünemann, Sophie Lehnerer, Sarah Hoffmann, Andreas Meisel   +14 more
wiley   +1 more source

A comparative evaluation of parafoveal and perifoveal macular vessel density loss in glaucoma using 3 × 3 mm OCTA scans. [PDF]

Sci Rep
Garcia Kahmeyer D, Mardin C, Lämmer R, Hohberger B, Schottenhamml J.   +4 more
europepmc   +1 more source

Changes in Immune‐Inflammation Status and Acute Ischemic Stroke Prognosis in Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Inflammation is a critical risk factor for poor outcomes in cerebral infarction. Prior studies focused primarily on baseline inflammation status, neglecting dynamic longitudinal changes. We try to investigate the association between immune‐inflammation status alterations and stroke prognosis, and evaluated three systemic biomarkers'
Songfang Chen, Wenting Huang, Yitian Liu, Xuan Chen, Buyu Ke, Qian Shen, Hanyu Cai, Jing Sun, Yan Li, Yungang Cao, Beilei Hu, Keyang Chen   +11 more
wiley   +1 more source

Microbial strategies for drought stress mitigation- a sustainable frontier in plant resilience. [PDF]

Front Plant Sci
Gahlot KD.
europepmc   +1 more source

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte, Lucy Norcliffe‐Kaufmann, Maria Luisa Cotrina, Zenith Khan, Kaia Dalamo, Patricio Millar Vernetti, Matthew Lawless, Elisabetta Morini, Monica Salani, Marla Weetall, Jana Narasimhan, Agostino G. Rocha, Susan A. Slaugenhaupt, Horacio Kaufmann   +13 more
wiley   +1 more source

ML-automated microfluidic circuit design. [PDF]

Sci Adv
Birtek MT, Aktas V, Aktas B, Abdullah AC, Ozcan A, Tasoglu S.   +5 more
europepmc   +1 more source

The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley   +1 more source

Unlocking the benefits of transparent and reusable science for climate risk management. [PDF]

Proc Natl Acad Sci U S A
Pollack AB, Auermuller L, Burleyson CD, Campbell J, Condon M, Cooper C, Coronese M, Dangendorf S, Doss-Gollin J, Hegde P, Helgeson C, Kopp RE, Kwakkel J, Lesk C, Mankin J, Nicholas RE, Rice J, Roth S, Srikrishnan V, Scheeler M, Tuana N, Vernon C, Zhao M, Keller K.   +23 more
europepmc   +1 more source