Results 251 to 260 of about 19,215,870 (318)

Potential Risk Factors for Lonely Death: A Nationwide Case-Control Study in Korea. [PDF]

J Korean Med Sci
Koo HY, Bai H, Lee JR, Kang MJ, Jun YH, Yun J, Sohn JH, Lee JY, Lee H.   +8 more
europepmc   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Exploring barriers and facilitators to achieving quality antenatal care in Ethiopia: a qualitative study. [PDF]

BMC Health Serv Res
Alemu AA, Welsh A, Getachew T, Khajehei M.   +3 more
europepmc   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Impact of a Digital Leakage Notification System on Leakage, Quality of Life, Healthcare Resource Utilisation, and Work Productivity: Interim Results from a Longitudinal Real-World Study in the UK. [PDF]

J Clin Med
Vestergaard M, Gunning A, Mather R, Hansen HD, Ajslev TA.   +4 more
europepmc   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Bridging the silver-digital divide: how digital literacy shapes diverse healthcare utilisation among China's older adults-a cross-sectional study in seven Chinese cities. [PDF]

Front Public Health
Zhang C, Hou J, Zhang H.
europepmc   +1 more source

Influence of the COVID-19 pandemic on drug and healthcare utilisation among First Nations with diabetes in Alberta, Canada: a retrospective cohort study. [PDF]

BMJ Open
Weaver O, Sarin C, Samanani S, Crowshoe L, Ye M, Eurich DT.   +5 more
europepmc   +1 more source

Healthcare utilisation among mothers of newborns with invasive group B <i>Streptococcus</i> disease: a 20-year national cohort study. [PDF]

BMJ Open
Lykke MR, Sørensen HTT, Lawn J, Horvath-Puho E.   +3 more
europepmc   +1 more source

Utilisation of healthcare in children born to lymphoma survivors in Sweden. [PDF]

Acta Oncol
Entrop JP, Wintzell V, Dietrich CE, Glimelius I, El-Galaly TC, Smedby KE, Eloranta S.   +6 more
europepmc   +1 more source