Results 111 to 120 of about 2,253,804 (251)

Research to Industry and Industry to Research

Detritus, 2018
Pivato Alberto, Pasetto Marco, Faleschini Flora, Beggio Giovanni, Hennebert Pierre   +4 more
openaire   +9 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

The way we do things matters: the deep integration of lived experience in the a/part of the crowd project to respond to loneliness in young adults. [PDF]

Res Involv Engagem
Peart C, Lewis M, Bibb J, Read G, Tesfu K, Rathore K, Tan LX, Wong T, Turner A, Andalib F, Ziero G, Rule J, Cao L, Merritt L, Rezaie N, Shelton T, Kaylor-Hughes C, Coe A, Orcher Muruwori/Gumbaynggirr P, Palmer VJ.   +19 more
europepmc   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Keuze uit de aanwinsten

The Rijksmuseum Bulletin, 2005
Rijksmuseum researchers
doaj   +3 more sources

Discovery of A <i>SLAMF1</i> Gene Change That Increases Dogs' Risk of Developing Canine Atopic Dermatitis: a Plain Language Summary. [PDF]

Vet Q
Forman OP, Freyer J, Kerr A, Labadie JD, Gow DJ, Alexander J.   +5 more
europepmc   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Aanwinsten

The Rijksmuseum Bulletin, 1954
Rijksmuseum researchers
doaj   +1 more source

Unique Challenges of Multidisciplinary Clinical Science: Perspectives from a Multidisciplinary Team. [PDF]

Clin Psychol Sci
Pokorny V, Damme K, Haase CM, Goldrick M, Mittal VA.   +4 more
europepmc   +1 more source