Results 151 to 160 of about 26,668,600 (298)
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Keuze uit de aanwinsten 1970 van het Rijksprentenkabinet
Rijksmuseum researchers
doaj +1 more source
Gender shapes the relationship between productivity and journal prestige in science. [PDF]
Ribeiro VH +4 more
europepmc +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Keuze uit de aanwinsten 1969 van het Rijksprentenkabinet
Rijksmuseum researchers
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Thinking Critically About Algorithms for Automated Detection of Behavior: 11 Guidelines for Social and Behavioral Scientists. [PDF]
de Barbaro K +2 more
europepmc +1 more source

