Results 171 to 180 of about 847,019 (319)

Impact of superior mesenteric artery (SMA) adherent tissue in the context of pancreatic head resections- an observational study. [PDF]

open access: yesBMC Cancer
Azizian A   +8 more
europepmc   +1 more source

Cancer‐Associated Fibroblasts Promote Tumor Immunosuppression in Hepatocellular Carcinoma via the NNMT‐ANGPTL4 Axis

open access: yesAdvanced Science, EarlyView.
ABSTRACT Background & Aims: Cancer‐associated fibroblasts (CAFs) drive immunosuppression in hepatocellular carcinoma (HCC). However, their metabolic regulation remains poorly defined. We investigated the role of nicotinamide N‐methyltransferase (NNMT) in CAFs. Approach & Results: High NNMT expression in CAF tissues was confirmed by western blotting and
Shounan Lu   +20 more
wiley   +1 more source

LAPAROSCOPIC RESECTION OF COLORECTAL LIVER METASTASES: A SINGLE CENTER CASE-CONTROL MATCHED-PAIRS ANALYSIS.

open access: yes, 2012
Background. This study is to evaluate overall results of liver surgery for colorectal liver metastases (CRLM) by comparing the open approach (OS) with the laparoscopic (LS) in a case-control matched pair analysis. Methods.
Cavaniglia D   +7 more
core  

Pharmacologic Modulation of ARID3A with Rimegepant Reactivates Type I Interferon Signaling and Sensitizes Triple‐Negative Breast Cancer to PD‐1 Blockade

open access: yesAdvanced Science, EarlyView.
This study identifies ARID3A as a key immunosuppressive transcription factor in TNBC. Its inhibition activates the type I IFN pathway, boosting CD8+ T cell infiltration and sensitizing tumors to anti‐PD‐1. The FDA‐approved migraine drug Rimegepant targets ARID3A, enhances immunotherapy efficacy in preclinical models, and establishes a druggable axis to
Teng Zhou   +12 more
wiley   +1 more source

Laparoscopic vs robotic minor liver resection of lesions located in the postero-superior segments: A comparative analysis

open access: yes, 2014
Introduction: Laparoscopic liver resection (LLR) is worldwide accepted as safe treatment option for anterior lesions of the liver. The approach of lesions located in the postero-superior (PS) segments (I-IVa-VII-VIII) is more difficult and usually ...
Roberto Montalti   +4 more
core  

Targeting Supramolecular Active Complexes of Nav1.7/Nav1.8 to Relieve Chronic Neuropathic Pain

open access: yesAdvanced Science, EarlyView.
In mice and patients with severe chronic neuropathic pain (NP), Nav1.7, Nav1.8, TrkB, and five cytoskeletal proteins form supramolecular active complexes (SMACs) with polygonal lattice structures as noxious signal amplifiers in dorsal root ganglion (DRG) neurons.
Liting Sun   +27 more
wiley   +1 more source

Endoscopic Intermuscular Dissection - Short-term Outcomes. [PDF]

open access: yesEndosc Int Open
Birzle L   +6 more
europepmc   +1 more source

Erratum : Does the revised cardiac risk index predict cardiac complications following elective lung resection? [PDF]

open access: yes, 2014
Pala Rajesh   +19 more
core   +1 more source

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