Results 221 to 230 of about 1,823,507 (396)

Increased liver regeneration rate and decreased liver function after synchronous liver and colon resection in rats [PDF]

open access: hybrid, 2009
Hideki Sasanuma   +6 more
openalex   +1 more source

Deacetylation of ACLY Mediates RNA M6A‐Modification of NOXA and Promotes Chemoresistance of Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
This study investigates the deacetylation of ACLY at K978 acts as a novel risk in colorectal cancer chemoresistance. The deacetylation of K978 induces ACLY relocation to the nucleus and promotes its binding to RBM15, a m6A methylation modification “writer”.
Jun Wen   +8 more
wiley   +1 more source

DYNLL1 binds to MRE11 to limit DNA end resection in BRCA1-deficient cells

open access: yesNature, 2018
Y. He   +18 more
semanticscholar   +1 more source

Prickle4 Drives Microenvironmental Remodeling and Resistance to Parp Inhibition in IDH‐Mutant Glioma

open access: yesAdvanced Science, EarlyView.
IDH‐mutant gliomas exhibit sensitivity to PARP inhibitors (PARPi) owing to oncometabolite 2‐HG‐induced DNA repair defects. PARPi treatment induces resistance by upregulating Prickle4, which promotes VEGF‐driven angiogenesis. Combining PARPi veliparib with anti‐angiogenic lenvatinib blocks this pathway, causing tumor regression and prolonged survival in
Ju Yang   +16 more
wiley   +1 more source

Recurrence and Outcomes Following Hepatic Resection, Radiofrequency Ablation, and Combined Resection/Ablation for Colorectal Liver Metastases

open access: yesAnnals of Surgery, 2004
E. Abdalla   +7 more
semanticscholar   +1 more source

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