METTL10‐Mediated PIAS3 Methylation Links Purine Metabolism to Gastric Cancer Progression
METTL10‐mediated methylation of PIAS3 at K442 inhibits its SUMO E3 ligase activity toward MITF. This reduces MITF SUMOylation and subsequent RNF4‐mediated ubiquitination, leading to MITF protein accumulation and gastric cancer progression. Abstract Metabolic dysregulation plays a significant role in the development of gastric cancer (GC).
Jinshui Tan +20 more
wiley +1 more source
Epileptogenic LGG surgery with seizure freedom purpose: Supratotal resection (ETT-SpTR) based on Electrocorticography and navigated transcranial magnetic stimulation. [PDF]
Battista F +13 more
europepmc +1 more source
To resect or not to resect: The decision in T1 esophageal adenocarcinoma [PDF]
openaire +3 more sources
Art. XIII.—Osteo-Sarcoma of the Lower Jaw.—Resection of the body of the bone.—Cure. [PDF]
Marion J. Simms
openalex +1 more source
Evaluation of the 2015 AGA guidelines on pancreatic cystic neoplasms in a large surgically confirmed multicenter cohort [PDF]
Early, Dayna S +4 more
core +2 more sources
This study introduces a miniaturized wireless neural recording system integrated with custom‐designed 120‐channel µECoG arrays, engineered for monitoring brain activities in freely behaving marmosets. The system can capture and characterize behavior‐specific neural signals, including drinking‐related activation, pre‐vocalization anticipatory responses,
Hongru Liu +22 more
wiley +1 more source
Endoscopic Submucosal Dissection for Gastroesophageal Reflux Disease-Related Neoplasms. [PDF]
Chen Z +9 more
europepmc +1 more source
The TIDE‐Cas14a system, an integrated RPA‐T7‐CRISPR/Cas14a cascade platform incorporating engineered crRNA mismatches, enables ultrasensitive detection of the PIK3CA H1047R mutation in breast cancer circulating tumor DNA, with a limit of detection as low as 0.01%, surpassing the sensitivity of droplet digital PCR.
Yuanyuan Yu +19 more
wiley +1 more source
The evolving role of wedge resection in early-stage non-small cell lung cancer: a literature review. [PDF]
Ceccarelli I +2 more
europepmc +1 more source

