Results 111 to 120 of about 17,351 (228)
Identification of relevant environmental descriptors [PDF]
Based on previous experiences and a literature review the most relevant environmental descriptors were selected and tested by means of field experiments.
Lantinga, Egbert
core
Formation of Condition‐Dependent Alpha‐Synuclein Fibril Strain in Artificial Cerebrospinal Fluid
α‐synuclein aggregation in artificial cerebrospinal fluid (aCSF) leads to a distinct conformation with an electron density pocket motif found in aggregates from PD and MSA patients. Such fibrils has low stability outside the reaction conditions, hinting about the influence of cerebrospinal fluid components not only on the formation, but also on the ...
Rūta Sniečkutė +7 more
wiley +1 more source
Controlling broad-leaved dock (Rumex obtusifolius) in grass clover mixtures [PDF]
This article describes three experiments on the control of broad-leaved dock. Experiment 1: Dock seeds were ensiled in grass silages of different dry matter percentages; 23, 34 and 60% respectively.
Fehér, L. +4 more
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In this article, Shuai and colleagues found that depletion of Sorcs3 could activate totipotency in mESCs, promising bidirectional differentiation potential to embryonic and extraembryonic lineages. The underlying mechanism might be activation of Tfap2c and repression of TGF‐β, PI3K‐AKT, and lysosome pathways.
Wenhao Zhang +12 more
wiley +1 more source
Managing the conversion process successfully [PDF]
The increase in numbers of farmers considering organic farming as a viable option will lead to an increase in the number of conversion plans to be prepared in the near future.
Barry, Pat, Swan , Brendan
core
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang +15 more
wiley +1 more source
The Phospholamban (PLN) R9C mutation reduces SERCA2a binding, increasing calcium recycling and baseline contractility. However, the excess of free PLN promotes pentamer formation, limiting phosphorylation and blunting β‐adrenergic signaling. Under cardiac stress, enhanced functional demands overwhelm proteostasis in PLN R9C cells, leading to misfolded ...
Qi Yu +10 more
wiley +1 more source
ABSTRACT Background Eosinophilic chronic rhinosinusitis with nasal polyps (eCRSwNP) is characterized by persistent sinonasal inflammation and marked eosinophilic infiltration. Although the relationship between eosinophils and NP formation has been extensively studied, the mechanisms governing eosinophil transepithelial migration into the nasal mucosa ...
Yeong‐In Jo +7 more
wiley +1 more source
Abstract INTRODUCTION Microglia are macrophage‐like brain resident immune cells known to express numerous Alzheimer's disease risk genes. Here we generated a human induced pluripotent stem cell (iPSC) derived microglia cell culture model for use in neuroimmune modeling and therapeutic testing.
Angela K. Haskell +16 more
wiley +1 more source
The first trials of rose clover in California were made in 1944 as part of Research Project 1194B. Rose clover, an annual reseeding legume, is well adapted to soils low in phosphate or sulfur and on which bur clover scarcely exists.
W Martin, W Williams, W Johnson
doaj

