Results 121 to 130 of about 17,351 (228)

Prosopis juliflora (sw.) DC in the drylands: A review of invasion, impacts and management in Eastern Africa

open access: yesSustainable Environment
Prosopis juliflora is a native tree species of Central and Southern America. Since its introduction in eastern Africa, P. juliflora has invaded most of the drylands with far-reaching negative effects on people’s livelihoods and the environment, amid ...
Josephat Mungoche   +5 more
doaj   +1 more source

Integrated Management: A Coastal Community Perspective [PDF]

open access: yes, 2010
This paper was prepared for the Food and Agriculture Organisation of the United Nations Regional Workshops on Small-Scale Fisheries "Securing Sustainable Small-Scale Fisheries: Bringing together responsible fisheries and social development".
Anthony Charles   +10 more
core  

ACSL3 Promotes Hepatocellular Carcinoma Tumorigenesis and Correlates With JAK–STAT3 Signaling

open access: yesCancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality with limited therapies. Reprogrammed lipid metabolism, driven by upregulated de novo lipogenesis, is a key tumorigenic mechanism. The enzyme ACSL3 is strongly correlated with poor HCC prognosis, positioning it as a potential therapeutic target.
Melika Amelimojarad   +3 more
wiley   +1 more source

MODELING ECONOMIC AND ECOLOGICAL BENEFITS OF POST-FIRE REVEGETATION IN THE GREAT BASIN [PDF]

open access: yes
This study employs a Markov chain model of vegetation dynamics to examine the economic and ecological benefits of post-fire revegetation in the Great Basin sagebrush steppe.
Englin, Jeffrey E.   +2 more
core   +1 more source

The ZNF148‐ZEB1‐AS1‐IGF2BP2‐NOD2 Axis Drives Microglial Antipneumococcal Immunity in Bacterial Meningitis

open access: yesGlia, Volume 74, Issue 2, February 2026.
ZNF148 upregulates ZEB1‐AS1, which scaffolds IGF2BP2 to stabilize NOD2 mRNA, enhancing microglial anti‐pneumococcal immunity via cytokine production and bacterial clearance in bacterial meningitis. ABSTRACT Streptococcus pneumoniae (Spn) meningitis remains a lethal central nervous system (CNS) infection with limited therapies. This study identifies the
Xiufu Hu   +6 more
wiley   +1 more source

Unconventional Secretion of Angiogenic Sonic Hedgehog–Containing Extra‐Large Extracellular Vesicles is Driven by PI3K–Rab18‐GDP Signalling

open access: yesJournal of Extracellular Biology, Volume 5, Issue 2, February 2026.
Human mesenchymal stem cells conditionally secrete sonic hedgehog (SHH)‐containing extra‐large extracellular vesicles (XLEVs) upon PI3K activation, which enriches the GDP‐bound form of Rab18. Rab18‐GDP drives perinuclear maturation and polarized vertical release of SHH‐XLEVs via Hsp90α‐ and nSMase2‐dependent mechanisms.
Shuo Wang   +3 more
wiley   +1 more source

Nanomedicine Strategies Against Biofilm‐Associated Infections: Advances, Challenges, and Translational Barriers

open access: yesMicrobiologyOpen, Volume 15, Issue 1, February 2026.
Explore the key challenges and limitations in nanomedicine for biofilm treatment, from drug loading efficiency to antimicrobial resistance. ABSTRACT Antimicrobial resistance continues to rise globally, with biofilm‐associated infections intensifying the clinical burden through persistent tolerance to antibiotics and evasion of immune responses ...
Husni Farah   +8 more
wiley   +1 more source

Mitochondrial Intercellular Transfer via Platelets After Physical Training Exerts Neuro‐Glial Protection Against Cerebral Ischemia

open access: yesMedComm, Volume 7, Issue 2, February 2026.
Treadmill training protects against white matter injury and reduces cerebral infarction. Muscle‐derived mitochondrial transfer via platelets is promoted by treadmill training. Platelet transfusion emerges as a potential low‐risk therapeutic strategy for sequelae and vascular dementia.
Toshiki Inaba   +8 more
wiley   +1 more source

Anomalies in Tournament Design: The Madness of March Madness [PDF]

open access: yes
Tournament design is of crucial importance in competitive sports. The primary goal of effective tournament design is to provide incentives for the participants to maximize their performance both during the tournament and in the time period leading up to ...
Cara Howe   +2 more
core   +3 more sources

Iterative Modeling via Structural Diffusion (IMSD): Exploring Fold‐Switching Pathways in Metamorphic Proteins Using AlphaFold2‐Based Generative Diffusion Model UFConf

open access: yesProteins: Structure, Function, and Bioinformatics, Volume 94, Issue 2, Page 633-648, February 2026.
ABSTRACT Metamorphic proteins (MPs) can fold into two or more distinct spatial structures. Increasing interest in MPs has spurred the search for computational tools to predict proteins fold‐switching potential and model their refolding pathways. Here we address this problem by using the recently reported generative diffusion predictor UFConf, based on ...
Dmitrii A. Luzik, Nikolai R. Skrynnikov
wiley   +1 more source

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