Results 131 to 140 of about 170,641 (296)

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

open access: yesFEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez   +4 more
wiley   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

open access: yesFEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan   +2 more
wiley   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

open access: yesFEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada   +7 more
wiley   +1 more source

Design and evaluation of FEBS Education and Training Academy module – Integrating generative artificial intelligence into life‐science education

open access: yesFEBS Open Bio, EarlyView.
Life‐science educators from 14 countries redesigned their own course materials with generative AI in a three‐session, pedagogy‐first FEBS Education and Training Academy workshop built on PICRAT. Among 12 matched respondents, four more reported high confidence in each of five practical domains, and 10 of 13 reported implementing at least one idea ...
Zvonimir Mlinarić, Ali Burak Özkaya
wiley   +1 more source

Resemblance and Representation

open access: yes, 2012
The thesis focuses on observation of resemblance, exploration of the identical and the different. At first, it considers analogy and comparation in a complex approach focusing on philosophy, logic, mathematics and linguistics.
Kliment, Jáchym
core  

Framing resemblance and expressiveness in music

open access: yes
This paper addresses James O. Young's and Nemesio Puy's critical assessments of Nelson Goodman's account of musical expressiveness. For that, I draw substantially on the work of Maria do Carmo d'Orey (1933-2023), an important although underrecognized ...
Guerreiro, Vítor
core   +1 more source

Nomological Resemblance

open access: yes, 2013
Laws of nature concern the natural properties of things. Newton’s law of gravity states that the gravitational force between objects is proportional to the product of their masses and inversely proportional to the square of their distance; Coulomb’s law ...
Stenwall, Robin   +2 more
core   +1 more source

Trait-dependent morphological resemblance of hybrids between female stone flounder (Kareius bicoloratus) and male starry flounder (Platichthys stellatus) to their parental species

open access: yesJournal of Animal Reproduction and Biotechnology
Background: Hybridization between closely related fish species can generate novel phenotypes that influence aquaculture performance. This study aimed to evaluate the morphological characteristics of hybrids between the two aquaculture-relevant flounder ...
Eun Jeong Kim   +3 more
doaj   +1 more source

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