Results 131 to 140 of about 170,641 (296)
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez +4 more
wiley +1 more source
A minimal cellulosome‐like system in Cellulosilyticum lentocellum
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan +2 more
wiley +1 more source
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada +7 more
wiley +1 more source
Life‐science educators from 14 countries redesigned their own course materials with generative AI in a three‐session, pedagogy‐first FEBS Education and Training Academy workshop built on PICRAT. Among 12 matched respondents, four more reported high confidence in each of five practical domains, and 10 of 13 reported implementing at least one idea ...
Zvonimir Mlinarić, Ali Burak Özkaya
wiley +1 more source
Resemblance and Representation
The thesis focuses on observation of resemblance, exploration of the identical and the different. At first, it considers analogy and comparation in a complex approach focusing on philosophy, logic, mathematics and linguistics.
Kliment, Jáchym
core
Framing resemblance and expressiveness in music
This paper addresses James O. Young's and Nemesio Puy's critical assessments of Nelson Goodman's account of musical expressiveness. For that, I draw substantially on the work of Maria do Carmo d'Orey (1933-2023), an important although underrecognized ...
Guerreiro, Vítor
core +1 more source
Laws of nature concern the natural properties of things. Newton’s law of gravity states that the gravitational force between objects is proportional to the product of their masses and inversely proportional to the square of their distance; Coulomb’s law ...
Stenwall, Robin +2 more
core +1 more source
Background: Hybridization between closely related fish species can generate novel phenotypes that influence aquaculture performance. This study aimed to evaluate the morphological characteristics of hybrids between the two aquaculture-relevant flounder ...
Eun Jeong Kim +3 more
doaj +1 more source

