Results 91 to 100 of about 715,165 (308)

Frederick K. Cox International Law Center dedication: Case Western Reserve University School of Law

open access: yes, 1994
Frederick K.
Case Western Reserve University School of Law
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Account of life of John Walworth

open access: yes
Walworth, John, account of his life by John BarrCleveland, Ohio and the Western Reserve Digital Text ...
Barr, John (Creatorcre)
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Dynamic neurocognitive adaptation in aging: Development and validation of a new scale

open access: yesAlzheimer’s & Dementia: Translational Research & Clinical Interventions
INTRODUCTION Forty‐five percent of Alzheimer's disease (AD) cases may have been preventable through protective factors. Reserve, resilience, and resistance share common neurocognitive adaptive processes, acting through protective mechanisms.
Filippo Cieri   +4 more
doaj   +1 more source

Account of the jollification upon the news of peace in 1815

open access: yes
Account of celebrations after War of 1812Cleveland, Ohio and the Western Reserve Digital Text ...
(Creatorcre)
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Account of James Kingsbury's:life, his family and neighbors, and life in early Cleveland

open access: yes
Description of James Kingsbury's life, family, neighbors, life in early Cleveland, and the hanging of John O'Mic on Public Square written by his daughterCleveland, Ohio and the Western Reserve Digital Text ...
Stedman, Diana (Creatorcre)
core  

The 5th Annual Case Western Reserve University School of Law Women’s Law & Leadership Conference (Part 3 of 3)

open access: yes, 2016
November 4, 2016 The 5th Annual Case Western Reserve University School of Law Women’s Law & Leadership Conference -- Part
Case Western Reserve University School of Law
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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