Results 111 to 120 of about 65,210 (292)
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Financial InnovationThis article investigates five safe-haven asset responses from 2014 to 2022, including the unprecedented COVID-19 crisis, Russian invasion of Ukraine, and sharp US interest rate increases of 2015 and 2022. We apply the unique approach of the multivariate
Ewa Feder-Sempach +2 more
doaj +1 more source
Dedollarization as a Direction of Russia's Financial Policy in Current Conditions. [PDF]
Stud Russ Econ Dev, 2023 Xu Wenhong.
europepmc +1 more source
Renminbi Rules: The Conditional Imminence of the Reserve Currency Transition [PDF]
Against the backdrop of the recent financial crisis and the ongoing rapid changes in the world economy, the fate of the dollar as the premier international reserve currency is under scrutiny.
Arvind Subramanian
core
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Improving data efficiency for analyzing global exchange rate fluctuations based on nonlinear causal network-based clustering. [PDF]
Ann Oper Res, 2022 Choi I, Yun W, Kim WC.
europepmc +1 more source
The Necessity of a Lower Dollar and the Route There [PDF]
, 2012 Debates over economic policy tend to be enormously confused. It is often the case that even high-level officials and well-known economists seem ignorant of basic accounting identities. This leads them to make claims that literally do not add up.
Dean Baker
core
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
International monetary system: issues and areas of reforms
Мир новой экономики, 2018 The article investigates issues of the modern international monetary system occurred due to dollar’s domination, and relevant forming risks for states members, and exams suggested measures for their elimination and solution.
V. V. Kuznetsova
doaj
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source