Results 61 to 70 of about 216,038 (307)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

The euro: It can't happen, It's a bad idea, It won't last. US economists on the EMU, 1989-2002 [PDF]

open access: yes
This study of approximately 170 publications shows (a) that US academic economists concentrated on the question "Is the EMU a good or bad thing?", usually adopting the paradigm of optimum currency areas as their main analytical vehicle, (b) that they ...
Eoin Drea, Lars Jonung
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Optimal use of scale economies in the Federal Reserve’s currency infrastructure [PDF]

open access: yes
Could the Federal Reserve lower its overall currency processing costs by reallocating its high-speed currency sorting volume? Given estimates of currency shipping costs and scale economies for high-speed sorting, the authors’ model minimizes costs by ...
Apostolos Burnetas   +3 more
core  

Can Chinese Yuan Become A Major Reserve Currency? [PDF]

open access: yes, 2016
After several years of efforts, especially on the part of the Chinese government, the International Monetary Fund (IMF) announced on November 30, 2015 that the Chinese currency, yuan (RMB or人民币), will be included into the Special Drawing Right (SDR ...
Wu, Congsheng
core  

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

The problems of the modern world monetary system

open access: yesХабаршысы. Экономика сериясы, 2016
The global monetary system has evolved in several successive stages. Each of them is characterized first of all by a definite form of global reserve assets. These reserve assets provide the turnover of all world trade and are a universal means of payment,
G. D. R. T. Dauliyeva Kalmakova
doaj  

Analyzing payment and settlement relations between Russia and China within the BRICS framework and the new reserve currency implementation

open access: yesВестник университета
The transformation of payment and settlement relations between Russia and China has been studied in the context of sanctions pressure and the desire to reduce dependence on the US dollar.
A. A. Chepkov
doaj   +1 more source

OPTIMAL GOVERNMENT FINANCE AND DEMOCRACY IN DEVELOPING COUNTRIES [PDF]

open access: yes
Optimal government finance models illustrating trade-offs between different policy instruments, such as seigniorage and income taxes, have focused on industrialized countries.
Renee D. Nieberding
core  

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