Results 121 to 130 of about 311,498 (288)

Estimating Foreign Exchange Reserve Adequacy

International Research Journal of Business Studies, 2013
Accumulating foreign exchange reserves, despite their cost and their impacts on other macroeconomics variables, provides some benefits. This paper models such foreign exchange reserves. To measure the adequacy of foreign exchange reserves for import, it uses total reserves-to-import ratio (TRM).
openaire   +3 more sources

Applying Hubbert Curves and Linearization to Rock Phosphate [PDF]

Rock phosphate is a critical, nonrenewable resource for which there is no known substitute in agriculture. Cordell, Drangert, and White (2009) use Hubbert methodology (1956) to estimate the peak--the year after which production will monotonically decline-
Cullen S. Hendrix
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Estimating the volume of glaciers in the Himalayan–Karakoram region using different methods [PDF]

, 2015
Ice volume estimates are crucial for assessing water reserves stored in glaciers. Due to its large glacier coverage, such estimates are of particular interest for the Himalayan–Karakoram (HK) region.
Bajracharya, S., Bolch, T., Frey, H., Huggel, C., Huss, Matthias, Kulkarni, A., Linsbauer, Andreas, Machguth, Horst, Salzmann, Nadine, Stoffel, Markus   +9 more
core  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Does Ecotourism in Nature Reserves Have an Impact on Farmers’ Income? Counterfactual Estimates Based on Propensity Score Matching

Agriculture
Farmers’ participation in ecological tourism management in nature reserves is an important way to increase income. Based on 921 pieces of household survey data from 44 villages in six nature reserves in Liaoning Province, this paper uses multiple linear ...
Ke Chen, Yujian Ping, Xinning Pan, Mingzhu Ye, Yang Wang   +4 more
doaj   +1 more source

ACTUARIAL ESTIMATION OF TECHNICAL RESERVES IN INSURANCE COMPANIES. BASIC CHAIN LADDER METHOD [PDF]

Annals of the University of Oradea: Economic Science, 2017
A major concern for insurance companies is to keep achieving financial stability of the insurance business which it carries. They must work in order to fully cover the expense of premiums collected, assumed obligations to policyholders. Otherwise, get in
Bențe Corneliu Cristian
doaj  

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Extracting Several Resource Deposits of Unknown Size: Optimal Order [PDF]

Oil companies often announce revised estimates of their reserves. This indicates that stock uncertainty is a prevalent feature of natural resource industries. In this paper we consider the multi-deposit case where resource extraction produces information
Murray C. Kemp, Ngo Van Long
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