Results 81 to 90 of about 311,498 (288)
Uncertainty and reserves in determination of dynamic machine loads acting on supporting structures [PDF]
Applied and Computational Mechanics, 2007 The reliability of dynamic loads for supporting structures. Machinery producers reserves´ and estimates of the loads determination. Reliability probabilistic indexing. Materials and loads characteristics and uncertainty of their determination.
Šmejkal J., Makovička D.
doaj
Large Hoardings of International Reserves: Are They Worth It? [PDF]
We empirically assess the contribution of international reserves vis- à -vis institutional variables in reducing the risk of a currency crisis. We find that the ratio of reserves to short-term debt is robust in explaining international crisis, even after
Claudio Soto, Pablo García
core
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Measuring Monetary Policy [PDF]
Extending the approach of Bernanke and Blinder (1992), Strongin (1992), and Christiano, Eichenbaum, and Evans (1994a, 1994b), we develop and apply a VAR-based methodology for measuring the stance of monetary policy.
Ben S. Bernanke, Ilian Mihov
core
Caspian oil in global context [PDF]
, 2006 This paper provides a brief overview of the political economy of Caspian oil. It begins by situating the Caspian region’s oil sectors in the larger global market, before proceeding to examine the ways in which the Azerbaijani, Turkmen and Kazakh oil ...
Tompson, William
core
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Vertical integration and value-relevance: Empirical evidence from oil and gas producers
Cogent Economics & Finance, 2016 Oil and gas exploration companies (E&Ps) exhibit large variations in earnings due to volatile oil and gas prices. Furthermore, their primary asset, oil and gas reserves, is accumulated through highly risky exploration activities.
Bård Misund
doaj +1 more source
The Impact of Monetary Policy on the Distribution and Type of Unemployment [PDF]
, 2004 This working paper by William M. Rodgers III employs two widely used approaches to estimate the effects of monetary policy on seven measures of unemployment.
William M. Rodgers
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source