Results 71 to 80 of about 1,246,962 (366)

Viral zoonotic risk is homogenous among taxonomic orders of mammalian and avian reservoir hosts

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2020
Significance Identifying whether novel human viruses disproportionately originate from certain animal groups could inform risk-based allocations of research and surveillance effort. Whether such “special reservoirs” exist remains controversial.
Nardus Mollentze, D. Streicker
semanticscholar   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Biological Stoichiometry Regulates Toxin Production in Microcystis aeruginosa (UTEX 2385)

open access: yesToxins, 2019
Harmful algal blooms (HABs) are increasing in magnitude, frequency, and duration globally. Even though a limited number of phytoplankton species can be toxic, they are becoming one of the greatest water quality threats to public health and ecosystems due
Nicole D. Wagner   +7 more
doaj   +1 more source

Reservoir computing using dynamic memristors for temporal information processing

open access: yesNature Communications, 2017
Reservoir computing systems utilize dynamic reservoirs having short-term memory to project features from the temporal inputs into a high-dimensional feature space.
Chao Du   +5 more
semanticscholar   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Soil to Sheath: Nocardia Flexor Tenosynovitis in an Immunocompetent Pottery Artist

open access: yesJournal of Hand Surgery Global Online
Stenosing flexing tenosynovitis (trigger finger) is a chronic, noninfectious condition of the flexor tendon sheath, whereas infectious flexor tenosynovitis is an acute hand infection that requires urgent recognition and treatment.
James Anundson, MS, BS   +2 more
doaj   +1 more source

Evaluation of the potential for carbon sink and association with land occupation

open access: yesJournal of Water and Climate Change, 2023
Anthropogenic influences on a global scale have caused negative impacts on the environment, among the most prominent being the increase in the concentration of carbon dioxide (CO2).
Fernando Yogi   +3 more
doaj   +1 more source

Identification of Splenic Reservoir Monocytes and Their Deployment to Inflammatory Sites

open access: yesScience, 2009
Monitoring Monocyte Reservoirs Monocytes are cells of the immune system that are recruited to sites of tissue injury and inflammation where they help to resolve the infection and are important for tissue repair.
F. Swirski   +14 more
semanticscholar   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

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