Results 41 to 50 of about 5,746,058 (301)

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Application of SVM algorithm in fluid prediction of volcanic reservoirs in Nanpu Sag, Bohai Bay Basin

Youqicang pingjia yu kaifa, 2023
Volcanic rock reservoirs are affected by many factors such as lithofacies, lithology, and reservoir space types, and fluid identification is difficult, which is one of the difficulties in well logging interpretation.
ZHANG Ying, QU Lili, ZHU Lu, ZHANG Yan, HAN Siyang, ZENG Cheng   +5 more
doaj  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Main controlling factors for oil and gas enrichment in Jurassic laminated shale in Fuxing area of Sichuan Basin

Shiyou shiyan dizhi
The Fuxing area of the Sichuan Basin is known for its multiple sets of organic-rich shale in the Jurassic period, with several wells yielding significant amounts of industrial oil and gas.
Daojun WANG, Chao CHEN, Zhujiang LIU, Shufan YANG, Miaomiao LIU, Jiatong XIE   +5 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Pore development characteristics and main controlling factors of tight oil reservoir in the seventh member of Triassic Yanchang Formation, Xunyi area, Ordos Basin

Shiyou shiyan dizhi
The seventh member of the Triassic Yanchang Formation (Chang 7 Member) in the Xunyi area of the Ordos Basin is a typical tight oil reservoir characterized by low porosity, low permeability, and strong heterogeneity.
Liangjun WANG, Xinxin YUE, Liansheng LI, Yanpeng WANG   +3 more
doaj   +1 more source

Characteristics and Affecting Factors of K₂qn¹ Member Shale Oil Reservoir in Southern Songliao Basin, China

Energies, 2022
Member 1 of the Cretaceous Qingshankou Formation (K2qn1 Member) in the Southern Songliao Basin, composed of mainly semi-deep and deep lacustrine shale layers, is rich in shale oil.
Zhongcheng Li, Zhidong Bao, Zhaosheng Wei, Hongxue Wang, Wanchun Zhao, Wentao Dong, Zheng Shen, Fan Wu, Wanting Tian, Lei Li   +9 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Structural and Reservoir Characteristics of Potential Carbon Dioxide Storage Sites in the Northern South Yellow Sea Basin, Offshore Eastern China

Journal of Marine Science and Engineering
The geological storage of carbon dioxide (CO2) in offshore saline aquifers stands as a primary option for reducing CO2 emissions in coastal regions. China’s coastal regions, particularly Shandong and Jiangsu provinces, face significant challenges in CO2 ...
Di Luo, Yong Yuan, Jianwen Chen, Qing Li, Jie Liang, Hualin Zhao   +5 more
doaj   +1 more source

A study on the characteristics and influencing factors of reservoir sedimentation in Wanjiazhai Reservoir [PDF]

MATEC Web of Conferences, 2018
Based on measured data of the Wanjiazhai Reservoir in different periods, the characteristics of the spatial and temporal distribution of sedimentation in the reservoir area were preliminarily analyzed and the impact of reservoir operation on this distribution was discussed.
Ren Zhihui, Wang Ting, Wang Yuanjian, Qu Shaojun   +3 more
openaire   +2 more sources