Results 31 to 40 of about 1,905,573 (291)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Prediction method of thin sand reservoir with coal bearing: An example from PB area of Xihu Sag at East China Sea

地质科技通报
In the sedimentary environment shaped by river-tidal bidirectional flow, thin coal seams are typically located within the oil- and gas-bearing strata of the Pinghu Formation in the PB area of the Xihu Sag.
Pan LUO, Jiusheng LI
doaj   +1 more source

Characteristics and prediction of permian tight glutenite reservoirs in dinan 15 well block, junggar basin

Frontiers in Earth Science, 2022
Glutenite reservoirs are characterized by rapid lateral change, strong heterogeneity, and complex main controlling factors. This research aims to identify macro and micro characteristics of glutenite reservoirs and establish criteria for identifying ...
Xin Wei, Xinming Sun, Xuejiao Yuan, Xuejiao Yuan, Yiming Yang, Yiming Yang   +5 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Analysis of factors influencing recovery of low permeability and strong heterogeneous gas reservoirs and establishment of prediction model

Frontiers in Earth Science, 2022
Jialingjiang Formation is a typical low permeability carbonate reservoir in Sichuan Basin, which is characterized by strong heterogeneity, low matrix permeability and high-water saturation.
Yi Zhao, Qingyan Mei, Xiaohong Yin, Kai Zhang, Xiang Zhao, Yuhan Yan, Dongming Zhang   +6 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Asymmetric Deep Co-Training Framework Using a Shape Context Descriptor for Reservoir Prediction: A Case Study from the Yinggehai Basin, South China Sea

Journal of Marine Science and Engineering
The scarcity and incompleteness of well-log data pose a critical challenge to deep learning-based reservoir prediction. To address this small-sample problem and improve prediction quality, we propose a novel semi-supervised asymmetric deep co-training ...
Xuanang Li, Jiao Xue, Hanming Gu
doaj   +1 more source

Reservoir Computing as a Tool for Climate Predictability Studies [PDF]

Journal of Advances in Modeling Earth Systems, 2021
<p>  Reduced-order dynamical models play a central role in developing our<br>  understanding of predictability of climate irrespective of whether<br>  we are dealing with the actual climate system or surrogate climate<br>  models. In this context,
openaire   +5 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source