Results 111 to 120 of about 83,703 (304)

Development of a Synthetic Hydrogel to Foster Microvascularization of an Endometriosis Microphysiological System

Advanced Healthcare Materials, EarlyView.
ABSTRACT The ascent of novel alternative methods in drug development spotlights the dual needs for improved biological fidelity to in vivo, along with reproducibility, especially in regulatory applications. The need for pre‐clinical models of patient‐derived endometriosis lesions motivates the development of a vascularizable, completely synthetic ...
Lauren Pruett, Laura Bahlmann, Ryan Ogi, Angela Jiao, Priyatanu Roy, Matthew Johnson, David Trumper, Linda Griffith   +7 more
wiley   +1 more source

Research Note:
An approach to integrated assessement of reservoir siltation: the Joaquín Costa reservoir as a case study

, 2004
International audienceIn 1932, the Esera river was dammed at the foothills of the Pyrenean External Ranges; since then, sedimentation has reduced its water storage capacity by a third.
Machín, J., Navas, A., Valero Garcés, B.   +2 more
core   +1 more source

Melt Electrowriting High Resolution Poly(ethylene‐co‐vinyl acetate) Scaffolds for Soft Tissue Engineering

Advanced Healthcare Materials, EarlyView.
This work pioneers melt electrowriting (MEW) of polyethylene vinyl acetate (PEVA) to fabricate ultra‐compliant, high‐resolution scaffolds. By integrating microscale precision with soft tissue‐like biomechanics, PEVA overcomes stiffness‐driven limitations of conventional MEW polymers, establishing a mechanically biomimetic platform for soft tissue ...
Finn Snow, Darcy De Rauch, Lilith Mabel Caballero Aguilar, Darcy Millett, Jasley Wilding McBride, David R Nisbet, Magdalena Kita, Elena Pirogova, Robert Michail Ivan Kapsa, Anita Quigley   +9 more
wiley   +1 more source

Assessing sediment-induced storage capacity loss in the Hisorak Reservoir, Uzbekistan

Watershed Ecology and the Environment
This study examines the long-term sedimentation dynamics and their impact on the storage capacity of the Hisorak Reservoir over 42 years (1980–2022). Sedimentation rates, capacity loss, and spatial volume changes were analyzed by comparing the original ...
Khojiakbar Khasanov, Masharif Bakiev
doaj   +1 more source

Reservoir sedimentation management with upstream sediment remanipulated

, 2020
Despite studies showing that dams have significant effects on the sediment dynamics and evolution of a river upstream of a dam, the knowledge on relationships between river topography and sediment transport in the dam’s backwater zone has been poorly applied in reservoir sedimentation management.
Li, T, Pasternack, GB
openaire   +2 more sources

Kajian Distribusi Sedimentasi Waduk Wonorejo, Tulungagung-Jawa Timur [PDF]

, 2011
This study aims to know the distribution of sedimentation of the most suitable method amongthe Emperical Area Reduction Method and Area Increment Method for predicting the the distributionof sediments in the Reservoir Wonorejo.
Setyono, E. (Ernawan)
core  

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

Advanced Healthcare Materials, EarlyView.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best, Gizem Karabiyik, Gerd Geerling, Sarah Barbara Zwingelberg, Gregor Lang, Martin Humenik   +5 more
wiley   +1 more source

Bioengineered 3D hPSC‐Cholangiocyte Ducts With Physiological Signals for Biliary Disease Modeling

Advanced Healthcare Materials, EarlyView.
Tian and colleagues generated a bioengineered bile duct from human pluripotent stem cell (hPSC)‐derived intrahepatic cholangiocytes within a high‐throughput, 384‐well platform to systematically examine the influence of biliary physiological signals including fluid flow, stromal cells and bile acids, and models intrahepatic biliary disease progression ...
Britney Tian, Mina Ogawa, Manami Kondo, Gabrielle Langeveld, Ling Jun Huan, Feng Zhang, Andrew Hollinger, Sara Deir, Christine Bear, Boyang Zhang, Shinichiro Ogawa   +10 more
wiley   +1 more source

A New 3D Colon on a Chip to Decipher the Influence of Mechanical Forces on the Physiological Cellular Ecosystem

Advanced Healthcare Materials, EarlyView.
To dissect how mechanical forces influence intestinal physiology, we developed a stretchable 3D colon‐on‐chip that integrates tunable topography, stiffness and peristalsis‐like motion within a physiologically relevant microenvironment. We showed that stretching is a dominant factor governing epithelial behavior, markedly enhancing proliferation and ...
Moencopi Bernheim‐Dennery, Lauriane Gérémie, Julie Brun, Lucas Chassatte, Giacomo Gropplero, Réda Bouras, Jieun Choo, Bertrand Cinquin, Alba Marcellan, Danijela Matic Vignjevic, Stéphanie Descroix   +10 more
wiley   +1 more source

Estimating Water Quality Benefits: Theoretical and Methodological Issues [PDF]

Knowledge of the benefits and costs to water users is required for a complete assessment of policies to create incentives for water quality improving changes in agricultural production.
Hellerstein, Daniel, Ribaudo, Marc
core   +1 more source