Results 31 to 40 of about 1,108 (210)

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Estimasi Volume Sedimentasi Waduk Sermo Menggunakan Metode RUSLE, Batimetri dan Angkutan Sedimen

Journal of Geospatial Information Science and Engineering, 2020
Sermo Reservoir is a reservoir which was built by Indonesian Government and supported by Asian Development Bank in program Integrated Irrigation Sector Project (IISP) in 1996. Sermo Reservoir functions as a flood control, raw water source and irrigation.
Annisa Wulandari, Bambang Kun Cahyono
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Modeling and training of hydraulic parameters affecting sedimentation [PDF]

Fanāvarī-i āmūzish, 2008
In this study, the numerical modeling of sediment washing in Sefidrood dam reservoir and its effect on reservoir volume recovery in the short and long term have been studied.
A. Shamsai, M. Ferasat kish
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Development of Protocol for Reservoir Sedimentation Prediction in Indonesia

International Journal of Technology
Dead storage of reservoir usually designed by soil erosion rate of catchment area result in certain year without considering land use and precipitation dynamic in the catchment and sedimentation distribution analysis at the bottom of the reservoir as ...
Arbor Reseda, Dwita Sutjiningsih, Setyo Sarwanto Moersidik   +2 more
doaj   +1 more source

Influence of Nile tilapia (Oreochromis niloticus) fish farming in net cages on the nutrient and particulate matter sedimentation rates in Umari reservoir, Brazilian semi-arid

Aquaculture Reports, 2020
This study evaluated the sedimentation rates of nutrients and particulate matter in Nile tilapia (Oreochromis niloticus) net cage farming in the Umari, Brazilian semi-arid reservoir.
Júlio César da Silva Cacho, Rodrigo Sávio Teixeira de Moura, Gustavo Gonzaga Henry-Silva   +2 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source