Results 31 to 40 of about 171,827 (218)
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
New Data on Biota of Some Lakes in the Western Part of the Putorana Plateau [PDF]
Species composition and abundance of zooplankton and zoobenthos of large Norilsk Lakes (Lama, Sobach’e) and Kutaramakan Lake in the western part of the Putorana plateau were studied in August-September of 2013–2014 after a long gap.
Vladimir A. Zadelenov +8 more
doaj
The data are presented showing that in the Achimov section deposits in the northern areas of West Siberia along with the porous type of reservoirs there occurred fractured-porous and porous-fractured types.
A. R. Kurchikov +4 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Study on the vertical well seepage model in composite carbonate reservoirs
Introduction: Carbonate reservoirs are widely distributed throughout the world. Due to the good physical properties of the reservoirs, they are easily contaminated by mud during drilling opening, so they are often put into production after acidification.
Chen Minjing +13 more
doaj +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
The heterogeneity of the Tahe fractured⁃vuggy reservoir is strong, and the fluid flow state is complex. The flow and waterflooding mechanisms of high⁃asphaltene heavy oil remain poorly understood, posing significant challenges to the effective ...
Lei LIU +6 more
doaj +1 more source
The objective and the main contribution of this issue are dedicated to using subsurface data to delineate a basin beneath the Gulf of Tunis and its neighbouring areas, and to investigate the potential of this area in terms of hydrocarbon resources ...
Dhraief Wissem +3 more
doaj +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source

